Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 12 studies | 34% ± 13% | |
| epithelial cell | 6 studies | 27% ± 14% | |
| adipocyte | 6 studies | 25% ± 6% | |
| fibroblast | 6 studies | 33% ± 22% | |
| kidney loop of Henle epithelial cell | 5 studies | 22% ± 2% | |
| Mueller cell | 5 studies | 32% ± 13% | |
| conventional dendritic cell | 4 studies | 44% ± 28% | |
| basal cell | 4 studies | 35% ± 28% | |
| dendritic cell | 4 studies | 47% ± 27% | |
| non-classical monocyte | 3 studies | 24% ± 9% | |
| retinal cone cell | 3 studies | 29% ± 7% | |
| retinal pigment epithelial cell | 3 studies | 30% ± 5% | |
| retinal rod cell | 3 studies | 25% ± 5% | |
| endothelial cell | 3 studies | 20% ± 4% | |
| melanocyte | 3 studies | 53% ± 27% | |
| hepatocyte | 3 studies | 39% ± 22% | |
| GABAergic neuron | 3 studies | 29% ± 8% | |
| glutamatergic neuron | 3 studies | 30% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 819.46 | 459 / 459 | 100% | 11.82 | 1114 / 1118 |
| prostate | 100% | 600.87 | 244 / 245 | 100% | 23.45 | 502 / 502 |
| brain | 100% | 1360.45 | 2630 / 2642 | 100% | 23.21 | 703 / 705 |
| intestine | 100% | 528.47 | 964 / 966 | 99% | 11.14 | 523 / 527 |
| esophagus | 99% | 491.76 | 1429 / 1445 | 99% | 12.88 | 182 / 183 |
| stomach | 99% | 569.16 | 354 / 359 | 100% | 11.63 | 285 / 286 |
| bladder | 100% | 468.43 | 21 / 21 | 98% | 10.06 | 495 / 504 |
| liver | 99% | 1125.79 | 224 / 226 | 96% | 18.47 | 391 / 406 |
| ovary | 96% | 421.22 | 172 / 180 | 100% | 16.00 | 429 / 430 |
| uterus | 97% | 388.31 | 165 / 170 | 97% | 11.22 | 447 / 459 |
| lung | 92% | 459.84 | 534 / 578 | 99% | 11.02 | 1144 / 1155 |
| skin | 92% | 431.16 | 1668 / 1809 | 98% | 11.65 | 464 / 472 |
| pancreas | 82% | 235.63 | 270 / 328 | 95% | 7.06 | 169 / 178 |
| thymus | 100% | 716.99 | 652 / 653 | 77% | 5.49 | 464 / 605 |
| adrenal gland | 96% | 381.23 | 247 / 258 | 79% | 5.12 | 181 / 230 |
| kidney | 100% | 735.70 | 89 / 89 | 67% | 3.77 | 607 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 13.88 | 29 / 29 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.26 | 1 / 1 |
| adipose | 100% | 845.99 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 99% | 380.88 | 238 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 8.75 | 44 / 45 |
| eye | 0% | 0 | 0 / 0 | 95% | 8.60 | 76 / 80 |
| muscle | 94% | 1673.77 | 756 / 803 | 0% | 0 | 0 / 0 |
| heart | 91% | 516.59 | 786 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 86% | 316.78 | 1148 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 37% | 238.34 | 343 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1903426 | Biological process | regulation of reactive oxygen species biosynthetic process |
| GO_0051881 | Biological process | regulation of mitochondrial membrane potential |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0034551 | Biological process | mitochondrial respiratory chain complex III assembly |
| GO_1990314 | Biological process | cellular response to insulin-like growth factor stimulus |
| GO_0007005 | Biological process | mitochondrion organization |
| GO_0031930 | Biological process | mitochondria-nucleus signaling pathway |
| GO_0032869 | Biological process | cellular response to insulin stimulus |
| GO_0000002 | Biological process | mitochondrial genome maintenance |
| GO_0030307 | Biological process | positive regulation of cell growth |
| GO_0006390 | Biological process | mitochondrial transcription |
| GO_0006864 | Biological process | pyrimidine nucleotide transport |
| GO_1990519 | Biological process | pyrimidine nucleotide import into mitochondrion |
| GO_0002082 | Biological process | regulation of oxidative phosphorylation |
| GO_0031966 | Cellular component | mitochondrial membrane |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0015218 | Molecular function | pyrimidine nucleotide transmembrane transporter activity |
| Gene name | SLC25A33 |
| Protein name | Solute carrier family 25 member 33 (Bone marrow stromal cell mitochondrial carrier protein) (BMSC-MCP) (HuBMSC-MCP) (Protein PNC1) |
| Synonyms | |
| Description | FUNCTION: Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Selectively transports uridine, thymidine, guanosine, cytosine and inosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism . May import (deoxy)nucleoside triphosphates in exchange for intramitochondrial (deoxy)nucleoside diphosphates, thus providing precursors necessary for de novo synthesis of mitochondrial DNA and RNA while exporting products of their catabolism . Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration . Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production . Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation . . |
| Accessions | ENST00000302692.7 Q9BSK2 |