Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 15 studies | 23% ± 4% | |
| classical monocyte | 9 studies | 23% ± 6% | |
| endothelial cell | 9 studies | 26% ± 9% | |
| type I pneumocyte | 7 studies | 22% ± 6% | |
| non-classical monocyte | 7 studies | 22% ± 7% | |
| monocyte | 6 studies | 19% ± 2% | |
| epithelial cell | 6 studies | 38% ± 17% | |
| ciliated cell | 6 studies | 31% ± 10% | |
| myeloid cell | 5 studies | 29% ± 5% | |
| fibroblast | 4 studies | 18% ± 1% | |
| dendritic cell | 4 studies | 29% ± 8% | |
| alveolar macrophage | 4 studies | 27% ± 8% | |
| endothelial cell of lymphatic vessel | 3 studies | 17% ± 1% | |
| conventional dendritic cell | 3 studies | 27% ± 3% | |
| pericyte | 3 studies | 19% ± 3% | |
| connective tissue cell | 3 studies | 19% ± 2% | |
| basal cell | 3 studies | 39% ± 4% | |
| transit amplifying cell | 3 studies | 29% ± 15% | |
| adipocyte | 3 studies | 20% ± 1% | |
| glutamatergic neuron | 3 studies | 30% ± 10% | |
| interneuron | 3 studies | 24% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1428.62 | 1445 / 1445 | 100% | 33.78 | 183 / 183 |
| ovary | 100% | 1508.74 | 180 / 180 | 100% | 28.20 | 430 / 430 |
| lung | 100% | 2368.29 | 578 / 578 | 99% | 23.63 | 1140 / 1155 |
| intestine | 100% | 2355.63 | 965 / 966 | 98% | 32.43 | 519 / 527 |
| breast | 100% | 2322.36 | 459 / 459 | 98% | 39.25 | 1099 / 1118 |
| stomach | 99% | 1232.31 | 356 / 359 | 98% | 33.12 | 281 / 286 |
| bladder | 100% | 1590.76 | 21 / 21 | 97% | 27.68 | 489 / 504 |
| uterus | 100% | 1692.73 | 170 / 170 | 96% | 24.88 | 439 / 459 |
| thymus | 100% | 1554.81 | 652 / 653 | 92% | 16.13 | 556 / 605 |
| kidney | 100% | 1108.48 | 89 / 89 | 89% | 17.84 | 803 / 901 |
| pancreas | 91% | 643.82 | 299 / 328 | 98% | 25.30 | 174 / 178 |
| skin | 99% | 2087.57 | 1797 / 1809 | 88% | 18.94 | 414 / 472 |
| prostate | 100% | 1063.17 | 244 / 245 | 84% | 10.04 | 423 / 502 |
| adrenal gland | 100% | 1791.38 | 258 / 258 | 60% | 6.11 | 139 / 230 |
| adipose | 100% | 2506.54 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1889.73 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1709.68 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.52 | 1 / 1 |
| heart | 95% | 849.56 | 819 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 19.45 | 42 / 45 |
| muscle | 90% | 598.50 | 725 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 11.87 | 24 / 29 |
| brain | 39% | 161.91 | 1030 / 2642 | 30% | 2.82 | 208 / 705 |
| peripheral blood | 64% | 618.23 | 598 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 49% | 5.35 | 39 / 80 |
| liver | 7% | 36.87 | 16 / 226 | 23% | 3.25 | 92 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015866 | Biological process | ADP transport |
| GO_1990544 | Biological process | mitochondrial ATP transmembrane transport |
| GO_0006839 | Biological process | mitochondrial transport |
| GO_0034599 | Biological process | cellular response to oxidative stress |
| GO_0051503 | Biological process | adenine nucleotide transport |
| GO_0071277 | Biological process | cellular response to calcium ion |
| GO_0015867 | Biological process | ATP transport |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0140987 | Molecular function | ATP:phosphate antiporter activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0140988 | Molecular function | ADP:phosphate antiporter activity |
| GO_0000295 | Molecular function | adenine nucleotide transmembrane transporter activity |
| GO_0005347 | Molecular function | ATP transmembrane transporter activity |
| Gene name | SLC25A24 |
| Protein name | Calcium-binding mitochondrial carrier protein SCaMC-1 (Solute carrier family 25 member 24) Mitochondrial adenyl nucleotide antiporter SLC25A24 (Mitochondrial ATP-Mg/Pi carrier protein 1) (Mitochondrial Ca(2+)-dependent solute carrier protein 1) (Short calcium-binding mitochondrial carrier protein 1) (SCaMC-1) (Solute carrier family 25 member 24) |
| Synonyms | MCSC1 SCAMC1 APC1 |
| Description | FUNCTION: Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways . In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides . May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates . . |
| Accessions | A0A3B3IU96 ENST00000640416.2 [Q6NUK1-1] H3BMI3 ENST00000569674.1 ENST00000639032.1 [Q6NUK1-2] ENST00000649955.1 ENST00000565488.6 [Q6NUK1-1] Q6NUK1 ENST00000370041.4 [Q6NUK1-2] ENST00000640018.1 ENST00000264128.13 ENST00000648874.1 ENST00000639606.1 J3KN42 |