SLC25A20 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC25A20 at tissue level.

III. Associated gene sets

GO_0006839Biological processmitochondrial transport
GO_1902616Biological processacyl carnitine transmembrane transport
GO_1902603Biological processcarnitine transmembrane transport
GO_0006853Biological processcarnitine shuttle
GO_0001701Biological processin utero embryonic development
GO_0005740Cellular componentmitochondrial envelope
GO_0005829Cellular componentcytosol
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0015227Molecular functionacyl carnitine transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC25A20
Protein nameSolute carrier family 25 member 20
Mitochondrial carnitine/acylcarnitine carrier protein (Carnitine/acylcarnitine translocase) (CAC) (CACT) (Solute carrier family 25 member 20)
SynonymsCAC
CACT
DescriptionFUNCTION: Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism (Probable). Key player in the mitochondrial oxidation pathway, it translocates the fatty acids in the form of acylcarnitines into the mitochondrial matrix, where the carnitine palmitoyltransferase 2 (CPT-2) activates them to undergo fatty acid beta-oxidation (Probable). Catalyzes the unidirectional transport (uniport) of carnitine at lower rates than the antiport (exchange) . .

AccessionsENST00000440964.1
ENST00000319017.5
C9JPE1
ENST00000430379.5
O43772
F8WEF6