SLC25A2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SLC25A2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC25A2 at tissue level.

III. Associated gene sets

GO_0006591Biological processornithine metabolic process
GO_1903826Biological processL-arginine transmembrane transport
GO_0000050Biological processurea cycle
GO_1990575Biological processmitochondrial L-ornithine transmembrane transport
GO_1903401Biological processL-lysine transmembrane transport
GO_1903352Biological processL-ornithine transmembrane transport
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0061459Molecular functionL-arginine transmembrane transporter activity
GO_0015189Molecular functionL-lysine transmembrane transporter activity
GO_0000064Molecular functionL-ornithine transmembrane transporter activity
GO_0015297Molecular functionantiporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC25A2
Protein nameMitochondrial ornithine transporter 2 (Solute carrier family 25 member 2)
SynonymsORC2
ORNT2
DescriptionFUNCTION: Mitochondrial transporter of the positively charged amino acids ornithine, lysine and arginine, and the neutral amino acid citrulline . In addition, transports the basic amino acids histidine, homoarginine, and asymmetric dimethylarginine (aDMA), but not symmetric DMA, and the D-forms of lysine, arginine, ornithine and histidine . Functions by both counter-exchange and uniport mechanisms . .

AccessionsENST00000239451.7
Q9BXI2