I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 25% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 25% ± 4% |
Insufficient scRNA-seq data for expression of SLC25A10 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 8124.54 | 226 / 226 | 99% | 34.01 | 403 / 406 |
| prostate | 96% | 1658.44 | 235 / 245 | 99% | 22.85 | 498 / 502 |
| breast | 98% | 1586.83 | 449 / 459 | 95% | 14.51 | 1065 / 1118 |
| stomach | 91% | 1599.21 | 325 / 359 | 94% | 18.37 | 269 / 286 |
| bladder | 86% | 843.95 | 18 / 21 | 97% | 20.96 | 487 / 504 |
| pancreas | 100% | 1834.28 | 328 / 328 | 81% | 8.08 | 145 / 178 |
| esophagus | 78% | 1327.57 | 1134 / 1445 | 97% | 12.24 | 177 / 183 |
| ovary | 78% | 407.06 | 141 / 180 | 96% | 11.97 | 414 / 430 |
| kidney | 100% | 5302.31 | 89 / 89 | 74% | 9.21 | 666 / 901 |
| intestine | 69% | 1456.49 | 663 / 966 | 95% | 24.07 | 501 / 527 |
| adrenal gland | 100% | 1271.12 | 258 / 258 | 61% | 4.67 | 141 / 230 |
| thymus | 99% | 994.21 | 645 / 653 | 61% | 4.82 | 367 / 605 |
| uterus | 58% | 296.81 | 98 / 170 | 95% | 15.99 | 438 / 459 |
| lung | 64% | 386.97 | 368 / 578 | 86% | 9.75 | 995 / 1155 |
| skin | 97% | 1315.05 | 1747 / 1809 | 40% | 2.82 | 190 / 472 |
| brain | 93% | 604.12 | 2448 / 2642 | 13% | 0.78 | 91 / 705 |
| ureter | 0% | 0 | 0 / 0 | 100% | 21.55 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 12.16 | 43 / 45 |
| adipose | 94% | 1409.37 | 1136 / 1204 | 0% | 0 | 0 / 0 |
| heart | 87% | 519.90 | 748 / 861 | 0% | 0 | 0 / 0 |
| spleen | 85% | 413.33 | 205 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 4.91 | 18 / 29 |
| muscle | 52% | 214.42 | 416 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 46% | 2.96 | 37 / 80 |
| peripheral blood | 27% | 361.12 | 255 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 14% | 81.44 | 193 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0035435 | Biological process | phosphate ion transmembrane transport |
| GO_0015729 | Biological process | oxaloacetate transport |
| GO_0006811 | Biological process | monoatomic ion transport |
| GO_0071422 | Biological process | succinate transmembrane transport |
| GO_0070221 | Biological process | sulfide oxidation, using sulfide:quinone oxidoreductase |
| GO_1902356 | Biological process | oxaloacetate(2-) transmembrane transport |
| GO_0046166 | Biological process | glyceraldehyde-3-phosphate biosynthetic process |
| GO_0008272 | Biological process | sulfate transport |
| GO_0015709 | Biological process | thiosulfate transport |
| GO_0006094 | Biological process | gluconeogenesis |
| GO_1902358 | Biological process | sulfate transmembrane transport |
| GO_0006835 | Biological process | dicarboxylic acid transport |
| GO_0071423 | Biological process | malate transmembrane transport |
| GO_0006869 | Biological process | lipid transport |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0015117 | Molecular function | thiosulfate transmembrane transporter activity |
| GO_0015116 | Molecular function | sulfate transmembrane transporter activity |
| GO_0015297 | Molecular function | antiporter activity |
| GO_0015131 | Molecular function | oxaloacetate transmembrane transporter activity |
| GO_0015141 | Molecular function | succinate transmembrane transporter activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005310 | Molecular function | dicarboxylic acid transmembrane transporter activity |
| GO_0015140 | Molecular function | malate transmembrane transporter activity |
| Gene name | SLC25A10 |
| Protein name | Solute carrier family 25 member 10 isoform 3 Solute carrier family 25 member 10 Solute carrier family 25 (Mitochondrial carrier dicarboxylate transporter), member 10, isoform CRA_a (Solute carrier family 25 member 10 isoform 1) Solute carrier family 25 member 10 isoform 2 Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10) |
| Synonyms | hCG_37927 DIC |
| Description | FUNCTION: Catalyzes the electroneutral exchange or flux of physiologically important metabolites such as dicarboxylates (malonate, malate, succinate), inorganic sulfur-containing anions, and phosphate, across mitochondrial inner membrane . Plays an important role in gluconeogenesis, fatty acid metabolism, urea synthesis, and sulfur metabolism, particularly in liver, by supplying the substrates for the different metabolic processes. Regulates fatty acid release from adipocytes, and contributes to systemic insulin sensitivity (By similarity). . |
| Accessions | A0A0S2Z3G3 A0A0S2Z382 ENST00000545862.5 Q9UBX3 I3L1E8 ENST00000331531.9 [Q9UBX3-2] F6RGN5 A0A0S2Z3I3 I3L3N9 ENST00000350690.10 [Q9UBX3-1] ENST00000574129.5 ENST00000574884.5 |
