Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| enterocyte | 7 studies | 36% ± 16% | |
| epithelial cell | 6 studies | 29% ± 5% | |
| epithelial cell of proximal tubule | 3 studies | 20% ± 4% | |
| brush cell | 3 studies | 18% ± 3% | |
| hepatocyte | 3 studies | 28% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 24% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 3099.26 | 89 / 89 | 96% | 31.01 | 866 / 901 |
| liver | 100% | 4066.12 | 226 / 226 | 96% | 53.98 | 388 / 406 |
| thymus | 100% | 1441.24 | 653 / 653 | 96% | 21.99 | 578 / 605 |
| skin | 99% | 1249.49 | 1799 / 1809 | 95% | 23.30 | 447 / 472 |
| intestine | 96% | 2494.06 | 924 / 966 | 98% | 37.38 | 515 / 527 |
| ovary | 97% | 480.75 | 175 / 180 | 96% | 19.05 | 412 / 430 |
| stomach | 96% | 949.92 | 346 / 359 | 95% | 30.31 | 273 / 286 |
| prostate | 100% | 1213.06 | 245 / 245 | 91% | 9.85 | 455 / 502 |
| lung | 99% | 854.40 | 572 / 578 | 92% | 17.43 | 1058 / 1155 |
| esophagus | 95% | 684.65 | 1374 / 1445 | 93% | 19.29 | 170 / 183 |
| pancreas | 97% | 404.71 | 317 / 328 | 90% | 25.72 | 161 / 178 |
| breast | 97% | 771.68 | 447 / 459 | 87% | 15.74 | 968 / 1118 |
| uterus | 99% | 595.49 | 168 / 170 | 84% | 12.26 | 387 / 459 |
| bladder | 95% | 712.62 | 20 / 21 | 86% | 17.98 | 434 / 504 |
| adrenal gland | 85% | 316.30 | 220 / 258 | 26% | 2.20 | 59 / 230 |
| eye | 0% | 0 | 0 / 0 | 100% | 35.30 | 80 / 80 |
| spleen | 100% | 1161.86 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 1310.02 | 919 / 929 | 0% | 0 | 0 / 0 |
| adipose | 98% | 670.09 | 1181 / 1204 | 0% | 0 | 0 / 0 |
| heart | 96% | 1081.41 | 825 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 11.41 | 40 / 45 |
| blood vessel | 88% | 420.06 | 1178 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 8.12 | 25 / 29 |
| brain | 29% | 105.04 | 778 / 2642 | 27% | 2.59 | 187 / 705 |
| muscle | 10% | 29.00 | 80 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006810 | Biological process | transport |
| GO_0006811 | Biological process | monoatomic ion transport |
| GO_0042908 | Biological process | xenobiotic transport |
| GO_1990961 | Biological process | xenobiotic detoxification by transmembrane export across the plasma membrane |
| GO_0015695 | Biological process | organic cation transport |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0042910 | Molecular function | xenobiotic transmembrane transporter activity |
| GO_0015293 | Molecular function | symporter activity |
| GO_0031625 | Molecular function | ubiquitin protein ligase binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SLC22A18 |
| Protein name | Solute carrier family 22 (Organic cation transporter), member 18, isoform CRA_a (Solute carrier family 22 member 18) Solute carrier family 22 member 18 (Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein) (Efflux transporter-like protein) (Imprinted multi-membrane-spanning polyspecific transporter-related protein 1) (Organic cation transporter-like protein 2) (ORCTL-2) (Solute carrier family 22 member 1-like) (Tumor-suppressing STF cDNA 5 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein) (p45-Beckwith-Wiedemann region 1 A) (p45-BWR1A) Solute carrier family 22 member 18 |
| Synonyms | ITM BWR1A ORCTL2 IMPT1 HET SLC22A1L TSSC5 hCG_16433 BWSCR1A |
| Description | FUNCTION: May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney. . |
| Accessions | ENST00000380574.5 ENST00000632784.1 A0A0J9YXN9 ENST00000485423.1 A0A024RCG2 ENST00000610526.4 ENST00000347936.6 E9PMN7 A0A0J9YWM3 E9PRM7 ENST00000622105.4 ENST00000631887.1 ENST00000449793.6 ENST00000649076.2 Q96BI1 ENST00000615661.2 |
