Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 14 studies | 48% ± 16% | |
oligodendrocyte precursor cell | 7 studies | 32% ± 13% | |
glutamatergic neuron | 6 studies | 44% ± 24% | |
astrocyte | 6 studies | 32% ± 12% | |
monocyte | 6 studies | 25% ± 5% | |
interneuron | 5 studies | 34% ± 18% | |
GABAergic neuron | 5 studies | 39% ± 19% | |
type II pneumocyte | 5 studies | 19% ± 4% | |
neuron | 4 studies | 40% ± 19% | |
endothelial cell | 3 studies | 37% ± 9% | |
granule cell | 3 studies | 19% ± 1% | |
ependymal cell | 3 studies | 30% ± 12% | |
alveolar macrophage | 3 studies | 34% ± 15% | |
fibroblast | 3 studies | 21% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 10 studies | 38% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 99% | 384.55 | 324 / 328 | 99% | 5.49 | 176 / 178 |
lung | 100% | 1167.29 | 577 / 578 | 95% | 4.73 | 1093 / 1155 |
breast | 96% | 404.98 | 441 / 459 | 92% | 4.93 | 1027 / 1118 |
esophagus | 89% | 547.30 | 1279 / 1445 | 98% | 6.24 | 179 / 183 |
kidney | 100% | 608.34 | 89 / 89 | 85% | 3.62 | 768 / 901 |
thymus | 99% | 559.57 | 649 / 653 | 84% | 2.15 | 508 / 605 |
brain | 100% | 1190.44 | 2636 / 2642 | 84% | 4.29 | 589 / 705 |
stomach | 96% | 430.26 | 345 / 359 | 86% | 3.22 | 246 / 286 |
prostate | 98% | 482.05 | 240 / 245 | 84% | 2.66 | 421 / 502 |
adrenal gland | 95% | 555.30 | 244 / 258 | 82% | 3.47 | 189 / 230 |
bladder | 86% | 374.19 | 18 / 21 | 88% | 3.71 | 442 / 504 |
intestine | 85% | 304.50 | 825 / 966 | 87% | 3.16 | 458 / 527 |
skin | 100% | 1250.30 | 1808 / 1809 | 70% | 3.30 | 332 / 472 |
uterus | 71% | 221.76 | 121 / 170 | 86% | 3.73 | 393 / 459 |
ovary | 68% | 193.51 | 123 / 180 | 65% | 1.45 | 280 / 430 |
spleen | 100% | 814.41 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.24 | 1 / 1 |
blood vessel | 100% | 676.54 | 1330 / 1335 | 0% | 0 | 0 / 0 |
adipose | 96% | 585.08 | 1161 / 1204 | 0% | 0 | 0 / 0 |
heart | 94% | 586.18 | 808 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 82% | 1043.75 | 765 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 80% | 2.93 | 36 / 45 |
liver | 25% | 106.95 | 56 / 226 | 53% | 2.83 | 215 / 406 |
lymph node | 0% | 0 | 0 / 0 | 66% | 1.45 | 19 / 29 |
eye | 0% | 0 | 0 / 0 | 45% | 0.92 | 36 / 80 |
muscle | 12% | 31.28 | 100 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006811 | Biological process | monoatomic ion transport |
GO_0015838 | Biological process | amino-acid betaine transport |
GO_0006865 | Biological process | amino acid transport |
GO_0008150 | Biological process | biological_process |
GO_0055085 | Biological process | transmembrane transport |
GO_0005575 | Cellular component | cellular_component |
GO_0005886 | Cellular component | plasma membrane |
GO_0015199 | Molecular function | amino-acid betaine transmembrane transporter activity |
GO_0003674 | Molecular function | molecular_function |
Gene name | SLC22A15 |
Protein name | Solute carrier family 22 member 15 (Fly-like putative transporter 1) (Flipt 1) Solute carrier family 22 member 15 isoform 7 Solute carrier family 22 member 15 isoform 5 Solute carrier family 22 member 15 isoform 4 Solute carrier family 22 member 15 isoform 2 (Solute carrier family 22 member 15 isoform 6) Solute carrier family 22 member 15 isoform 1 |
Synonyms | UNQ9429/PRO34686 FLIPT1 |
Description | FUNCTION: Organic zwitterion/cation transporter with apparent specificity for amino acids and their derivatives. Has low affinity for its substrates and may regulate their flux across the plasma membrane at high substrate concentrations . Bidirectionally transports carnitine and acetylcarnitine, possibly regulating their cytosolic abundance and further fatty acid catabolism via beta oxidation . Displays high transport activity toward zwitterionic substrates such as glycine betaine and diet-derived ergothioneine and carnosine. Can transport cations having an indole skeleton such as thiamine with lower efficiency. Does not transport agmatine . The transport mechanism, symport with sodium or facilitated diffusion allosterically regulated by sodium, remains to be elucidated (Probable). . |
Accessions | ENST00000369503.9 [Q8IZD6-1] A0A0S2Z6C8 A0A0S2Z5J2 A0A0S2Z5M4 A0A0S2Z5P9 Q8IZD6 ENST00000369502.1 [Q8IZD6-2] A0A0S2Z5R0 |