SLC1A7 | OmnibusX

Name	Number of supported studies	Average coverage
eye	6 studies	22% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	95%	441.12	915 / 966	48%	3.46	252 / 527
bladder	100%	506.48	21 / 21	38%	3.97	192 / 504
lung	98%	373.35	568 / 578	39%	9.28	456 / 1155
stomach	71%	398.79	256 / 359	55%	3.73	157 / 286
breast	98%	523.87	452 / 459	26%	0.48	289 / 1118
prostate	93%	400.12	227 / 245	22%	0.33	108 / 502
uterus	99%	509.39	168 / 170	12%	0.50	55 / 459
esophagus	87%	664.67	1258 / 1445	22%	0.84	40 / 183
brain	54%	195.53	1419 / 2642	55%	1.62	387 / 705
liver	64%	152.23	145 / 226	40%	5.75	163 / 406
ovary	100%	905.20	180 / 180	3%	0.05	13 / 430
ureter	0%	0	0 / 0	100%	1.11	1 / 1
adipose	99%	737.23	1192 / 1204	0%	0	0 / 0
thymus	90%	348.18	589 / 653	3%	0.05	19 / 605
blood vessel	89%	351.23	1191 / 1335	0%	0	0 / 0
heart	72%	273.34	616 / 861	0%	0	0 / 0
pancreas	9%	12.36	29 / 328	61%	1.72	109 / 178
skin	53%	118.86	966 / 1809	2%	0.04	9 / 472
kidney	34%	89.71	30 / 89	17%	0.74	154 / 901
muscle	49%	180.67	390 / 803	0%	0	0 / 0
peripheral blood	31%	84.29	290 / 929	0%	0	0 / 0
spleen	22%	29.27	52 / 241	0%	0	0 / 0
adrenal gland	19%	31.89	49 / 258	0%	0.02	1 / 230
eye	0%	0	0 / 0	18%	1.49	14 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45

GO_0015813	Biological process	L-glutamate transmembrane transport
GO_0006811	Biological process	monoatomic ion transport
GO_0015804	Biological process	neutral amino acid transport
GO_0001504	Biological process	neurotransmitter uptake
GO_1902476	Biological process	chloride transmembrane transport
GO_0006835	Biological process	dicarboxylic acid transport
GO_0006836	Biological process	neurotransmitter transport
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0097060	Cellular component	synaptic membrane
GO_0098794	Cellular component	postsynapse
GO_0005886	Cellular component	plasma membrane
GO_0015175	Molecular function	neutral L-amino acid transmembrane transporter activity
GO_0015501	Molecular function	glutamate:sodium symporter activity
GO_0005314	Molecular function	high-affinity L-glutamate transmembrane transporter activity
GO_0008068	Molecular function	extracellularly glutamate-gated chloride channel activity
GO_0005313	Molecular function	L-glutamate transmembrane transporter activity

Gene name	SLC1A7
Protein name	Amino acid transporter Excitatory amino acid transporter 5 (Retinal glutamate transporter) (Solute carrier family 1 member 7)
Synonyms	EAAT5
Description	FUNCTION: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion . Acts primarily as an inhibitory glutamate-gated chloride channel being a major inhibitory presynaptic receptor at mammalian rod bipolar cell axon terminals. Glutamate binding gates a large Cl(-) conductance that mediates inhibition, affecting visual processing in the retina (By similarity). .
Accessions	ENST00000611397.5 F1T0D3 ENST00000620288.4 F1T0D2 F1T0D4 ENST00000620347.5 L0C9Y3 O00341 ENST00000371494.9 [O00341-1] ENST00000371491.4 [O00341-2] ENST00000649098.1 A0A087WUF9

SLC1A7 report