I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 20% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 20% ± 4% |
Insufficient scRNA-seq data for expression of SLC16A6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 419.94 | 2590 / 2642 | 78% | 3.50 | 547 / 705 |
| breast | 78% | 314.43 | 358 / 459 | 88% | 37.85 | 981 / 1118 |
| lung | 97% | 566.74 | 559 / 578 | 54% | 2.55 | 625 / 1155 |
| skin | 75% | 276.53 | 1352 / 1809 | 67% | 35.27 | 314 / 472 |
| thymus | 72% | 132.96 | 469 / 653 | 65% | 2.93 | 395 / 605 |
| adrenal gland | 91% | 417.55 | 235 / 258 | 30% | 1.56 | 69 / 230 |
| esophagus | 44% | 526.70 | 642 / 1445 | 58% | 2.87 | 107 / 183 |
| spleen | 100% | 758.23 | 241 / 241 | 0% | 0 | 0 / 0 |
| kidney | 28% | 57.85 | 25 / 89 | 72% | 5.77 | 646 / 901 |
| peripheral blood | 99% | 1166.00 | 924 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 6.70 | 27 / 29 |
| eye | 0% | 0 | 0 / 0 | 90% | 22.54 | 72 / 80 |
| muscle | 82% | 512.43 | 658 / 803 | 0% | 0 | 0 / 0 |
| ovary | 46% | 83.13 | 82 / 180 | 32% | 1.09 | 136 / 430 |
| tonsil | 0% | 0 | 0 / 0 | 73% | 4.14 | 33 / 45 |
| uterus | 26% | 49.58 | 44 / 170 | 47% | 2.58 | 217 / 459 |
| adipose | 71% | 245.28 | 855 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 38% | 45.95 | 8 / 21 | 32% | 1.56 | 159 / 504 |
| pancreas | 2% | 3.85 | 8 / 328 | 52% | 2.10 | 92 / 178 |
| intestine | 28% | 51.62 | 272 / 966 | 21% | 0.81 | 109 / 527 |
| stomach | 18% | 26.73 | 65 / 359 | 23% | 0.94 | 65 / 286 |
| prostate | 20% | 30.96 | 50 / 245 | 17% | 0.65 | 87 / 502 |
| heart | 31% | 67.37 | 266 / 861 | 0% | 0 | 0 / 0 |
| liver | 18% | 27.54 | 40 / 226 | 11% | 0.52 | 44 / 406 |
| blood vessel | 20% | 46.09 | 267 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0015718 | Biological process | monocarboxylic acid transport |
| GO_0015734 | Biological process | taurine transmembrane transport |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005368 | Molecular function | taurine transmembrane transporter activity |
| GO_0008028 | Molecular function | monocarboxylic acid transmembrane transporter activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SLC16A6 |
| Protein name | Monocarboxylate transporter 7 (MCT 7) (Monocarboxylate transporter 6) (MCT 6) (Solute carrier family 16 member 6) SLC16A6 protein Solute carrier family 16 member 6 |
| Synonyms | MCT6 MCT7 |
| Description | FUNCTION: Monocarboxylate transporter selective for taurine. May associate with BSG/CD147 or EMB/GP70 ancillary proteins to mediate facilitative efflux or influx of taurine across the plasma membrane. The transport is pH- and sodium-independent. Rather low-affinity, is likely effective for taurine transport in tissues where taurine is present at high concentrations. . |
| Accessions | J3KTN2 J3KS02 A1L175 ENST00000580666.6 O15403 A1L174 ENST00000327268.8 ENST00000582867.1 ENST00000583477.5 |
