SLC16A10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006590Biological processthyroid hormone generation
GO_0015823Biological processphenylalanine transport
GO_0070327Biological processthyroid hormone transport
GO_0003333Biological processamino acid transmembrane transport
GO_0015828Biological processtyrosine transport
GO_0006865Biological processamino acid transport
GO_0015718Biological processmonocarboxylic acid transport
GO_0070460Biological processthyroid-stimulating hormone secretion
GO_0015827Biological processtryptophan transport
GO_0015801Biological processaromatic amino acid transport
GO_0005886Cellular componentplasma membrane
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0030054Cellular componentcell junction
GO_0016323Cellular componentbasolateral plasma membrane
GO_0015171Molecular functionamino acid transmembrane transporter activity
GO_0015349Molecular functionthyroid hormone transmembrane transporter activity
GO_0005302Molecular functionL-tyrosine transmembrane transporter activity
GO_0015196Molecular functionL-tryptophan transmembrane transporter activity
GO_0008028Molecular functionmonocarboxylic acid transmembrane transporter activity
GO_0015173Molecular functionaromatic amino acid transmembrane transporter activity
GO_0015192Molecular functionL-phenylalanine transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC16A10
Protein nameSLC16A10 protein
Solute carrier family 16 member 10
Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1)
PRO0813 (Solute carrier family 16 member 10)
SynonymsTAT1
MCT10
DescriptionFUNCTION: Sodium- and proton-independent thyroid hormones and aromatic acids transporter . Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels . Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa) . Plays an important role in homeostasis of aromatic amino acids (By similarity). .

AccessionsENST00000368850.4
Q8TF71
ENST00000419619.2
Q05BR4
ENST00000368851.10
ENST00000439288.5
H0Y3W8
H0Y5M8
Q9P1I2