Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 14 studies | 31% ± 14% | |
| myeloid cell | 6 studies | 25% ± 9% | |
| glutamatergic neuron | 5 studies | 37% ± 16% | |
| GABAergic neuron | 4 studies | 46% ± 14% | |
| oligodendrocyte precursor cell | 4 studies | 21% ± 3% | |
| endothelial cell | 3 studies | 21% ± 7% | |
| epithelial cell | 3 studies | 40% ± 23% | |
| dendritic cell | 3 studies | 17% ± 0% | |
| fibroblast | 3 studies | 20% ± 2% | |
| alveolar macrophage | 3 studies | 39% ± 8% | |
| monocyte | 3 studies | 19% ± 4% | |
| interneuron | 3 studies | 31% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 35% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 2739.37 | 328 / 328 | 74% | 2.50 | 131 / 178 |
| thymus | 89% | 327.28 | 581 / 653 | 74% | 2.71 | 449 / 605 |
| lung | 88% | 702.69 | 511 / 578 | 68% | 1.96 | 791 / 1155 |
| kidney | 99% | 599.43 | 88 / 89 | 56% | 1.75 | 509 / 901 |
| liver | 92% | 647.41 | 208 / 226 | 56% | 1.72 | 226 / 406 |
| adrenal gland | 100% | 1177.53 | 258 / 258 | 38% | 1.77 | 87 / 230 |
| stomach | 79% | 905.15 | 282 / 359 | 58% | 2.04 | 166 / 286 |
| skin | 72% | 1336.86 | 1295 / 1809 | 61% | 1.94 | 287 / 472 |
| prostate | 45% | 139.17 | 111 / 245 | 58% | 1.13 | 293 / 502 |
| muscle | 100% | 5169.53 | 803 / 803 | 0% | 0 | 0 / 0 |
| intestine | 32% | 96.93 | 313 / 966 | 58% | 1.52 | 308 / 527 |
| spleen | 79% | 339.46 | 190 / 241 | 0% | 0 | 0 / 0 |
| brain | 44% | 194.27 | 1154 / 2642 | 35% | 1.19 | 247 / 705 |
| ovary | 32% | 80.17 | 58 / 180 | 42% | 1.06 | 182 / 430 |
| esophagus | 6% | 19.03 | 82 / 1445 | 56% | 1.48 | 102 / 183 |
| heart | 53% | 180.19 | 456 / 861 | 0% | 0 | 0 / 0 |
| bladder | 10% | 36.62 | 2 / 21 | 43% | 1.19 | 216 / 504 |
| adipose | 47% | 369.17 | 566 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 4% | 12.23 | 6 / 170 | 40% | 1.20 | 184 / 459 |
| blood vessel | 41% | 230.45 | 547 / 1335 | 0% | 0 | 0 / 0 |
| breast | 21% | 98.48 | 97 / 459 | 19% | 0.47 | 210 / 1118 |
| eye | 0% | 0 | 0 / 0 | 39% | 1.05 | 31 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 36% | 0.79 | 16 / 45 |
| peripheral blood | 22% | 125.36 | 208 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 21% | 0.75 | 6 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006590 | Biological process | thyroid hormone generation |
| GO_0015823 | Biological process | phenylalanine transport |
| GO_0070327 | Biological process | thyroid hormone transport |
| GO_0003333 | Biological process | amino acid transmembrane transport |
| GO_0015828 | Biological process | tyrosine transport |
| GO_0006865 | Biological process | amino acid transport |
| GO_0015718 | Biological process | monocarboxylic acid transport |
| GO_0070460 | Biological process | thyroid-stimulating hormone secretion |
| GO_0015827 | Biological process | tryptophan transport |
| GO_0015801 | Biological process | aromatic amino acid transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0030054 | Cellular component | cell junction |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0015171 | Molecular function | amino acid transmembrane transporter activity |
| GO_0015349 | Molecular function | thyroid hormone transmembrane transporter activity |
| GO_0005302 | Molecular function | L-tyrosine transmembrane transporter activity |
| GO_0015196 | Molecular function | L-tryptophan transmembrane transporter activity |
| GO_0008028 | Molecular function | monocarboxylic acid transmembrane transporter activity |
| GO_0015173 | Molecular function | aromatic amino acid transmembrane transporter activity |
| GO_0015192 | Molecular function | L-phenylalanine transmembrane transporter activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SLC16A10 |
| Protein name | SLC16A10 protein Solute carrier family 16 member 10 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) PRO0813 (Solute carrier family 16 member 10) |
| Synonyms | TAT1 MCT10 |
| Description | FUNCTION: Sodium- and proton-independent thyroid hormones and aromatic acids transporter . Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels . Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa) . Plays an important role in homeostasis of aromatic amino acids (By similarity). . |
| Accessions | ENST00000368850.4 Q8TF71 ENST00000419619.2 Q05BR4 ENST00000368851.10 ENST00000439288.5 H0Y3W8 H0Y5M8 Q9P1I2 |