Insufficient scRNA-seq data for expression of SLC14A2 at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 268.59 | 258 / 258 | 24% | 1.34 | 55 / 230 |
| thymus | 94% | 74.98 | 613 / 653 | 24% | 3.64 | 148 / 605 |
| lung | 96% | 26.50 | 552 / 578 | 12% | 2.32 | 136 / 1155 |
| kidney | 97% | 197.39 | 86 / 89 | 8% | 0.37 | 76 / 901 |
| breast | 91% | 73.69 | 417 / 459 | 13% | 0.62 | 141 / 1118 |
| adipose | 98% | 100.63 | 1180 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 93% | 25.04 | 228 / 245 | 4% | 0.07 | 21 / 502 |
| blood vessel | 97% | 37.62 | 1298 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 93% | 19.15 | 225 / 241 | 0% | 0 | 0 / 0 |
| brain | 43% | 6.91 | 1141 / 2642 | 26% | 1.26 | 185 / 705 |
| skin | 60% | 13.94 | 1086 / 1809 | 1% | 0.02 | 6 / 472 |
| bladder | 57% | 6.33 | 12 / 21 | 4% | 0.44 | 19 / 504 |
| muscle | 57% | 10.85 | 457 / 803 | 0% | 0 | 0 / 0 |
| heart | 57% | 10.38 | 487 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 54% | 10.71 | 502 / 929 | 0% | 0 | 0 / 0 |
| esophagus | 50% | 8.09 | 717 / 1445 | 3% | 0.36 | 6 / 183 |
| intestine | 42% | 8.06 | 406 / 966 | 6% | 0.20 | 32 / 527 |
| uterus | 38% | 4.22 | 65 / 170 | 4% | 0.19 | 17 / 459 |
| stomach | 35% | 4.21 | 124 / 359 | 7% | 0.61 | 20 / 286 |
| ovary | 26% | 3.21 | 46 / 180 | 7% | 0.64 | 30 / 430 |
| liver | 24% | 3.02 | 54 / 226 | 8% | 0.28 | 33 / 406 |
| pancreas | 16% | 1.51 | 53 / 328 | 1% | 0.01 | 1 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.23 | 4 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0015840 | Biological process | urea transport |
| GO_0071918 | Biological process | urea transmembrane transport |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0050839 | Molecular function | cell adhesion molecule binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0015204 | Molecular function | urea transmembrane transporter activity |
| Gene name | SLC14A2 |
| Protein name | Solute carrier family 14 (Urea transporter), member 2, isoform CRA_a (cDNA FLJ23656 fis, clone COLF1004, highly similar to Mus musculus urea transporter isoform UTA-3 mRNA) Urea transporter 2 (Solute carrier family 14 member 2) (Urea transporter, kidney) Solute carrier family 14 member 2 |
| Synonyms | HUT2 UT2 hCG_2021009 |
| Description | FUNCTION: [Isoform 1]: Mediates the transport of urea driven by a concentration gradient across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism. .; FUNCTION: [Isoform 2]: Mediates the transport of urea driven by a concentration gradient across the cell membrane of the kidney inner medullary collecting duct which is critical to the urinary concentrating mechanism. . |
| Accessions | Q8TEC4 ENST00000586448.5 [Q15849-1] ENST00000323329.3 Q15849 E7EPU1 ENST00000255226.11 [Q15849-1] |
