SLC13A2 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	4 studies	29% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC13A2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	98%	1975.30	87 / 89	30%	5.00	272 / 901
intestine	49%	2848.95	477 / 966	60%	8.80	315 / 527
breast	53%	366.10	242 / 459	54%	6.24	599 / 1118
skin	62%	470.77	1114 / 1809	2%	0.08	8 / 472
stomach	0%	1.19	1 / 359	62%	10.75	178 / 286
liver	16%	15.81	36 / 226	44%	8.15	178 / 406
pancreas	2%	3.96	6 / 328	47%	5.92	83 / 178
esophagus	1%	4.16	21 / 1445	24%	3.90	44 / 183
lung	2%	3.29	12 / 578	20%	3.72	235 / 1155
bladder	0%	0	0 / 21	21%	2.95	108 / 504
ovary	1%	0.69	1 / 180	20%	2.15	87 / 430
thymus	0%	0.16	1 / 653	14%	0.69	87 / 605
uterus	1%	0.65	1 / 170	12%	1.46	53 / 459
tonsil	0%	0	0 / 0	9%	0.57	4 / 45
adrenal gland	0%	1.75	1 / 258	7%	0.22	16 / 230
prostate	2%	13.85	4 / 245	4%	0.16	21 / 502
adipose	2%	12.17	27 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	1%	0.02	1 / 80
muscle	0%	0.56	4 / 803	0%	0	0 / 0
blood vessel	0%	0.35	3 / 1335	0%	0	0 / 0
brain	0%	0.04	1 / 2642	0%	0.05	1 / 705
heart	0%	0.21	1 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071422	Biological process	succinate transmembrane transport
GO_0015742	Biological process	alpha-ketoglutarate transport
GO_0015741	Biological process	fumarate transport
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0071285	Biological process	cellular response to lithium ion
GO_0016324	Cellular component	apical plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0015139	Molecular function	alpha-ketoglutarate transmembrane transporter activity
GO_0015361	Molecular function	low-affinity sodium:dicarboxylate symporter activity
GO_0015141	Molecular function	succinate transmembrane transporter activity
GO_0015138	Molecular function	fumarate transmembrane transporter activity
GO_0017153	Molecular function	sodium:dicarboxylate symporter activity
GO_0005515	Molecular function	protein binding

Gene name	SLC13A2
Protein name	SLC13A2 protein Solute carrier family 13 member 2 (Na(+)/dicarboxylate cotransporter 1) (NaDC-1) (Renal sodium/dicarboxylate cotransporter) Solute carrier family 13 (Sodium-dependent dicarboxylate transporter), member 2 Solute carrier family 13 member 2
Synonyms	SDCT1 NADC1
Description	FUNCTION: Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small intestine and renal proximal tubule . Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic . Citrate is transported in protonated form as a divalent anion, rather than the trivalent form which is normally found in blood . Has a critical role in renal dicarboxylate transport (By similarity). .
Accessions	Q4VAR9 ENST00000579281.5 J3QR70 ENST00000314669.10 [Q13183-1] ENST00000459818.2 Q8IV67 ENST00000444914.7 [Q13183-3] Q13183 J3QL78

SLC13A2 report