Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 7 studies | 22% ± 3% | |
endothelial cell | 6 studies | 26% ± 9% | |
retina horizontal cell | 5 studies | 35% ± 6% | |
ciliated cell | 4 studies | 26% ± 8% | |
epithelial cell | 4 studies | 28% ± 9% | |
cardiac muscle cell | 3 studies | 16% ± 1% | |
dendritic cell | 3 studies | 26% ± 6% | |
brush cell | 3 studies | 21% ± 4% |
Insufficient scRNA-seq data for expression of SLC12A7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 9882.09 | 226 / 226 | 100% | 71.11 | 405 / 406 |
kidney | 100% | 10410.03 | 89 / 89 | 99% | 104.56 | 895 / 901 |
stomach | 100% | 5631.68 | 359 / 359 | 99% | 89.64 | 284 / 286 |
prostate | 100% | 5745.50 | 245 / 245 | 99% | 49.88 | 498 / 502 |
thymus | 100% | 7143.86 | 653 / 653 | 99% | 40.89 | 600 / 605 |
breast | 100% | 5348.97 | 459 / 459 | 99% | 67.22 | 1106 / 1118 |
intestine | 100% | 6074.11 | 966 / 966 | 98% | 79.24 | 519 / 527 |
lung | 100% | 6315.63 | 577 / 578 | 98% | 84.67 | 1137 / 1155 |
pancreas | 100% | 4207.55 | 327 / 328 | 98% | 81.33 | 175 / 178 |
ovary | 100% | 3115.06 | 180 / 180 | 98% | 55.93 | 421 / 430 |
bladder | 100% | 3861.52 | 21 / 21 | 96% | 57.17 | 483 / 504 |
esophagus | 97% | 3188.68 | 1400 / 1445 | 96% | 90.68 | 175 / 183 |
uterus | 100% | 3977.62 | 170 / 170 | 90% | 47.69 | 411 / 459 |
adrenal gland | 100% | 3648.55 | 258 / 258 | 77% | 23.10 | 176 / 230 |
skin | 86% | 3026.90 | 1547 / 1809 | 79% | 32.26 | 372 / 472 |
brain | 83% | 1789.32 | 2202 / 2642 | 58% | 14.55 | 410 / 705 |
adipose | 100% | 4849.18 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 9141.93 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 21.63 | 1 / 1 |
heart | 100% | 9080.01 | 859 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 52.97 | 79 / 80 |
blood vessel | 96% | 2267.33 | 1288 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 84% | 62.72 | 38 / 45 |
lymph node | 0% | 0 | 0 / 0 | 79% | 22.29 | 23 / 29 |
peripheral blood | 78% | 2265.00 | 721 / 929 | 0% | 0 | 0 / 0 |
muscle | 37% | 616.59 | 297 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006811 | Biological process | monoatomic ion transport |
GO_0055064 | Biological process | chloride ion homeostasis |
GO_0071333 | Biological process | cellular response to glucose stimulus |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0006884 | Biological process | cell volume homeostasis |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0055075 | Biological process | potassium ion homeostasis |
GO_0140157 | Biological process | ammonium import across plasma membrane |
GO_1990573 | Biological process | potassium ion import across plasma membrane |
GO_0071805 | Biological process | potassium ion transmembrane transport |
GO_0032991 | Cellular component | protein-containing complex |
GO_0045202 | Cellular component | synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0019901 | Molecular function | protein kinase binding |
GO_0015379 | Molecular function | potassium:chloride symporter activity |
GO_0008519 | Molecular function | ammonium channel activity |
Gene name | SLC12A7 |
Protein name | Solute carrier family 12 member 7 Alternative protein SLC12A7 Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) |
Synonyms | KCC4 |
Description | FUNCTION: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling . May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity). . |
Accessions | H0YB78 ENST00000634447.1 A0A0G2JQE3 A0A0U1RR18 ENST00000264930.10 [Q9Y666-1] A0A0U1RR10 ENST00000628680.1 ENST00000513223.2 ENST00000611005.3 A0A0G2JNW7 Q9Y666 L8E7W0 ENST00000504576.2 |