Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 28% ± 11% | |
| endothelial cell | 3 studies | 20% ± 4% | |
| ciliated cell | 3 studies | 21% ± 2% | |
| GABAergic neuron | 3 studies | 27% ± 5% | |
| glutamatergic neuron | 3 studies | 32% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 23% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 1699.97 | 459 / 459 | 100% | 25.19 | 1118 / 1118 |
| esophagus | 100% | 1635.80 | 1445 / 1445 | 100% | 28.26 | 183 / 183 |
| intestine | 100% | 1796.12 | 966 / 966 | 100% | 18.47 | 527 / 527 |
| ovary | 100% | 1593.41 | 180 / 180 | 100% | 26.44 | 430 / 430 |
| stomach | 100% | 1288.06 | 359 / 359 | 100% | 21.27 | 286 / 286 |
| uterus | 100% | 1740.65 | 170 / 170 | 100% | 25.01 | 459 / 459 |
| brain | 100% | 1345.93 | 2639 / 2642 | 100% | 22.38 | 705 / 705 |
| lung | 100% | 1454.38 | 576 / 578 | 100% | 22.14 | 1155 / 1155 |
| bladder | 100% | 1526.33 | 21 / 21 | 100% | 20.60 | 502 / 504 |
| prostate | 100% | 1459.73 | 245 / 245 | 99% | 16.94 | 498 / 502 |
| thymus | 100% | 1691.27 | 653 / 653 | 99% | 15.70 | 600 / 605 |
| kidney | 100% | 1676.71 | 89 / 89 | 98% | 16.14 | 884 / 901 |
| pancreas | 100% | 1073.49 | 327 / 328 | 98% | 15.81 | 175 / 178 |
| liver | 100% | 1375.52 | 226 / 226 | 97% | 11.08 | 392 / 406 |
| adrenal gland | 100% | 1583.18 | 258 / 258 | 96% | 12.14 | 220 / 230 |
| skin | 100% | 2222.61 | 1809 / 1809 | 93% | 20.67 | 439 / 472 |
| adipose | 100% | 1818.37 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 17.71 | 29 / 29 |
| spleen | 100% | 1858.76 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 22.61 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.31 | 1 / 1 |
| blood vessel | 100% | 1529.49 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1156.95 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 99% | 1092.94 | 851 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 83% | 1196.22 | 770 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 56% | 5.40 | 45 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0035331 | Biological process | negative regulation of hippo signaling |
| GO_0005829 | Cellular component | cytosol |
| GO_0090443 | Cellular component | FAR/SIN/STRIPAK complex |
| GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0031267 | Molecular function | small GTPase binding |
| Gene name | SIKE1 |
| Protein name | Suppressor of IKBKE 1 (Suppressor of IKK-epsilon) |
| Synonyms | SIKE |
| Description | FUNCTION: Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and RIGI. Does not inhibit NF-kappa-B activation pathways. . |
| Accessions | Q9BRV8 ENST00000369528.9 [Q9BRV8-2] ENST00000060969.6 [Q9BRV8-1] |
