SIGLEC5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SIGLEC5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SIGLEC5 at tissue level.

III. Associated gene sets

GO_0007155Biological processcell adhesion
GO_0030667Cellular componentsecretory granule membrane
GO_0070821Cellular componenttertiary granule membrane
GO_0005886Cellular componentplasma membrane
GO_0101003Cellular componentficolin-1-rich granule membrane
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding
GO_0033691Molecular functionsialic acid binding

IV. Literature review

[source]
Gene nameSIGLEC5
Protein nameSialic acid-binding Ig-like lectin 5 (Siglec-5) (CD33 antigen-like 2) (Obesity-binding protein 2) (OB-BP2) (OB-binding protein 2) (CD antigen CD170)
SynonymsCD33L2
OBBP2
DescriptionFUNCTION: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

AccessionsO15389
ENST00000683636.1