I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| enterocyte | 7 studies | 50% ± 14% | |
| epithelial cell | 4 studies | 30% ± 9% | |
| goblet cell | 3 studies | 27% ± 9% | |
| progenitor cell | 3 studies | 30% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| enterocyte | 7 studies | 50% ± 14% | |
| epithelial cell | 4 studies | 30% ± 9% | |
| goblet cell | 3 studies | 27% ± 9% | |
| progenitor cell | 3 studies | 30% ± 2% |
Insufficient scRNA-seq data for expression of SI at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 54% | 5210.63 | 523 / 966 | 45% | 10.34 | 238 / 527 |
| prostate | 11% | 12.43 | 27 / 245 | 40% | 5.57 | 200 / 502 |
| stomach | 1% | 1.63 | 3 / 359 | 49% | 12.24 | 139 / 286 |
| esophagus | 1% | 7.26 | 9 / 1445 | 24% | 21.40 | 44 / 183 |
| pancreas | 0% | 0 | 0 / 328 | 16% | 5.53 | 29 / 178 |
| bladder | 0% | 0 | 0 / 21 | 13% | 1.50 | 64 / 504 |
| lung | 0% | 0.30 | 1 / 578 | 7% | 2.99 | 81 / 1155 |
| liver | 0% | 0.25 | 1 / 226 | 2% | 0.63 | 8 / 406 |
| uterus | 1% | 0.79 | 1 / 170 | 2% | 1.08 | 8 / 459 |
| skin | 0% | 0.51 | 6 / 1809 | 1% | 0.07 | 6 / 472 |
| breast | 1% | 3.68 | 6 / 459 | 0% | 0.00 | 1 / 1118 |
| ovary | 1% | 0.52 | 1 / 180 | 0% | 0.01 | 1 / 430 |
| adipose | 0% | 0.28 | 4 / 1204 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.20 | 8 / 2642 | 0% | 0 | 0 / 705 |
| blood vessel | 0% | 0.26 | 4 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.06 | 1 / 803 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.06 | 1 / 861 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.00 | 1 / 901 |
| peripheral blood | 0% | 0.08 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0 | 0 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0005987 | Biological process | sucrose catabolic process |
| GO_0044245 | Biological process | polysaccharide digestion |
| GO_0005903 | Cellular component | brush border |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004574 | Molecular function | oligo-1,6-glucosidase activity |
| GO_0004558 | Molecular function | alpha-1,4-glucosidase activity |
| GO_0004575 | Molecular function | sucrose alpha-glucosidase activity |
| GO_0030246 | Molecular function | carbohydrate binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SI |
| Protein name | Sucrase-isomaltase Sucrase-isomaltase, intestinal [Cleaved into: Sucrase (EC 3.2.1.48); Isomaltase (EC 3.2.1.10)] |
| Synonyms | |
| Description | FUNCTION: Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides. . |
| Accessions | ENST00000476593.1 F8WF21 ENST00000264382.8 P14410 |
