Name | Number of supported studies | Average coverage | |
---|---|---|---|
type I pneumocyte | 7 studies | 23% ± 4% | |
epithelial cell | 6 studies | 33% ± 15% | |
ciliated cell | 4 studies | 28% ± 11% | |
ionocyte | 3 studies | 38% ± 6% | |
secretory cell | 3 studies | 29% ± 13% | |
basal cell | 3 studies | 36% ± 10% | |
transit amplifying cell | 3 studies | 26% ± 12% | |
oligodendrocyte precursor cell | 3 studies | 19% ± 1% |
Insufficient scRNA-seq data for expression of SH2D4A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 1286.06 | 577 / 578 | 98% | 28.15 | 1135 / 1155 |
pancreas | 100% | 1000.87 | 328 / 328 | 96% | 33.23 | 171 / 178 |
liver | 100% | 1332.01 | 225 / 226 | 96% | 20.64 | 389 / 406 |
thymus | 100% | 1149.68 | 653 / 653 | 95% | 45.95 | 574 / 605 |
prostate | 96% | 759.00 | 234 / 245 | 99% | 18.54 | 498 / 502 |
ovary | 98% | 2164.04 | 177 / 180 | 95% | 18.42 | 410 / 430 |
stomach | 91% | 1433.43 | 326 / 359 | 98% | 30.52 | 281 / 286 |
kidney | 100% | 1033.75 | 89 / 89 | 88% | 16.01 | 796 / 901 |
bladder | 90% | 924.71 | 19 / 21 | 97% | 30.29 | 487 / 504 |
breast | 98% | 526.09 | 452 / 459 | 87% | 21.42 | 969 / 1118 |
esophagus | 88% | 1014.19 | 1271 / 1445 | 95% | 23.16 | 173 / 183 |
intestine | 64% | 486.83 | 620 / 966 | 98% | 28.09 | 519 / 527 |
uterus | 62% | 211.72 | 105 / 170 | 96% | 28.02 | 439 / 459 |
skin | 100% | 1217.83 | 1807 / 1809 | 47% | 8.57 | 222 / 472 |
adrenal gland | 100% | 1118.37 | 258 / 258 | 18% | 3.24 | 42 / 230 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.45 | 1 / 1 |
adipose | 98% | 591.28 | 1177 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 36.59 | 43 / 45 |
spleen | 83% | 248.81 | 199 / 241 | 0% | 0 | 0 / 0 |
heart | 63% | 204.40 | 539 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 53% | 152.58 | 705 / 1335 | 0% | 0 | 0 / 0 |
brain | 17% | 36.86 | 438 / 2642 | 26% | 2.57 | 183 / 705 |
eye | 0% | 0 | 0 / 0 | 38% | 2.92 | 30 / 80 |
peripheral blood | 11% | 37.66 | 106 / 929 | 0% | 0 | 0 / 0 |
muscle | 1% | 3.06 | 12 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0019902 | Molecular function | phosphatase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SH2D4A |
Protein name | SH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38) SH2 domain containing 4A |
Synonyms | PPP1R38 SH2A |
Description | FUNCTION: Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. . |
Accessions | ENST00000265807.8 [Q9H788-1] ENST00000518040.5 [Q9H788-2] ENST00000523736.1 Q9H788 H0YAT1 ENST00000519207.5 [Q9H788-1] |