SH2D4A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SH2D4A at tissue level.

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0019902Molecular functionphosphatase binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSH2D4A
Protein nameSH2 domain-containing protein 4A (Protein SH(2)A) (Protein phosphatase 1 regulatory subunit 38)
SH2 domain containing 4A
SynonymsPPP1R38
SH2A
DescriptionFUNCTION: Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. .

AccessionsENST00000265807.8 [Q9H788-1]
ENST00000518040.5 [Q9H788-2]
ENST00000523736.1
Q9H788
H0YAT1
ENST00000519207.5 [Q9H788-1]