SGSM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090630Biological processactivation of GTPase activity
GO_0005829Cellular componentcytosol
GO_0005794Cellular componentGolgi apparatus
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_0005737Cellular componentcytoplasm
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameSGSM1
Protein nameSmall G protein signaling modulator 1
Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2)
SynonymsRUTBC2
KIAA1941
DescriptionFUNCTION: Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as a GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B. .

AccessionsENST00000400358.9 [Q2NKQ1-4]
ENST00000400359.4 [Q2NKQ1-1]
ENST00000610372.4
A0A087X241
Q2NKQ1