I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 17% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 17% ± 2% |
Insufficient scRNA-seq data for expression of SGSH at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 2107.85 | 328 / 328 | 100% | 16.51 | 178 / 178 |
| prostate | 100% | 4290.82 | 245 / 245 | 100% | 42.57 | 502 / 502 |
| skin | 100% | 3689.43 | 1809 / 1809 | 100% | 34.82 | 472 / 472 |
| thymus | 100% | 4220.46 | 653 / 653 | 100% | 28.06 | 604 / 605 |
| stomach | 100% | 2562.06 | 359 / 359 | 100% | 16.96 | 285 / 286 |
| lung | 100% | 4429.41 | 578 / 578 | 100% | 20.92 | 1150 / 1155 |
| adrenal gland | 100% | 8301.71 | 258 / 258 | 100% | 38.64 | 229 / 230 |
| ovary | 100% | 2343.31 | 180 / 180 | 100% | 17.76 | 428 / 430 |
| kidney | 100% | 3055.36 | 89 / 89 | 99% | 22.32 | 896 / 901 |
| breast | 100% | 3615.78 | 459 / 459 | 99% | 22.97 | 1110 / 1118 |
| intestine | 100% | 2885.11 | 966 / 966 | 99% | 17.43 | 521 / 527 |
| uterus | 100% | 2865.33 | 170 / 170 | 99% | 17.98 | 453 / 459 |
| esophagus | 100% | 2460.33 | 1445 / 1445 | 98% | 17.51 | 180 / 183 |
| bladder | 100% | 2892.33 | 21 / 21 | 98% | 20.61 | 494 / 504 |
| liver | 100% | 1244.30 | 225 / 226 | 96% | 11.20 | 389 / 406 |
| brain | 79% | 867.61 | 2094 / 2642 | 100% | 15.75 | 705 / 705 |
| adipose | 100% | 3049.49 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 33.21 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 16.48 | 29 / 29 |
| spleen | 100% | 6277.39 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 12.77 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 29.85 | 1 / 1 |
| blood vessel | 100% | 2495.77 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 2718.86 | 922 / 929 | 0% | 0 | 0 / 0 |
| heart | 97% | 1297.36 | 836 / 861 | 0% | 0 | 0 / 0 |
| muscle | 86% | 745.61 | 687 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030200 | Biological process | heparan sulfate proteoglycan catabolic process |
| GO_0061744 | Biological process | motor behavior |
| GO_0006027 | Biological process | glycosaminoglycan catabolic process |
| GO_0008340 | Biological process | determination of adult lifespan |
| GO_0043202 | Cellular component | lysosomal lumen |
| GO_0005764 | Cellular component | lysosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0008484 | Molecular function | sulfuric ester hydrolase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016250 | Molecular function | N-sulfoglucosamine sulfohydrolase activity |
| Gene name | SGSH |
| Protein name | N-sulfoglucosamine sulfohydrolase N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) |
| Synonyms | HSS |
| Description | FUNCTION: Catalyzes a step in lysosomal heparan sulfate degradation. . |
| Accessions | I3L4B7 ENST00000572257.5 I3L2L4 I3L2I6 ENST00000570923.1 P51688 I3L207 ENST00000326317.11 I3NI22 ENST00000576941.5 ENST00000576856.1 ENST00000574505.5 I3L0M2 ENST00000576707.5 ENST00000573150.5 ENST00000570427.1 A0A286RZ45 I3L4C9 I3L3T3 |
