SFXN5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034220Biological processmonoatomic ion transmembrane transport
GO_0006865Biological processamino acid transport
GO_0015746Biological processcitrate transport
GO_1990542Biological processmitochondrial transmembrane transport
GO_0120162Biological processpositive regulation of cold-induced thermogenesis
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0015137Molecular functioncitrate transmembrane transporter activity
GO_0015075Molecular functionmonoatomic ion transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSFXN5
Protein nameSideroflexin 5
Sideroflexin-5
Synonyms
DescriptionFUNCTION: Mitochondrial amino-acid transporter (By similarity). Transports citrate (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity). In brown adipose tissue, plays a role in the regulation of UCP1-dependent thermogenesis probably by supporting mitochondrial glycerol-3-phosphate utilization (By similarity). .

AccessionsENST00000411783.5
B8ZZJ6
ENST00000450185.5
H7C1S9
C9JIV5
ENST00000410065.5
ENST00000442582.1
Q8TD22
ENST00000272433.7
F8WBH6