Insufficient scRNA-seq data for expression of SETSIP at single-cell level.
Insufficient scRNA-seq data for expression of SETSIP at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 79% | 3.65 | 1145 / 1445 | 52% | 0.86 | 96 / 183 |
| ovary | 87% | 4.16 | 156 / 180 | 37% | 0.58 | 159 / 430 |
| brain | 90% | 6.02 | 2367 / 2642 | 21% | 0.47 | 147 / 705 |
| stomach | 73% | 2.64 | 262 / 359 | 35% | 0.68 | 101 / 286 |
| intestine | 81% | 3.43 | 786 / 966 | 21% | 0.33 | 109 / 527 |
| lung | 83% | 4.29 | 479 / 578 | 10% | 0.16 | 121 / 1155 |
| skin | 86% | 5.04 | 1558 / 1809 | 3% | 0.05 | 16 / 472 |
| uterus | 84% | 3.59 | 143 / 170 | 4% | 0.04 | 17 / 459 |
| thymus | 82% | 3.54 | 535 / 653 | 1% | 0.02 | 6 / 605 |
| muscle | 82% | 3.50 | 659 / 803 | 0% | 0 | 0 / 0 |
| adrenal gland | 81% | 3.49 | 210 / 258 | 0% | 0 | 0 / 230 |
| adipose | 81% | 3.46 | 970 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 80% | 3.04 | 192 / 241 | 0% | 0 | 0 / 0 |
| breast | 77% | 3.37 | 355 / 459 | 2% | 0.03 | 21 / 1118 |
| blood vessel | 79% | 3.21 | 1048 / 1335 | 0% | 0 | 0 / 0 |
| bladder | 67% | 2.14 | 14 / 21 | 5% | 0.08 | 25 / 504 |
| pancreas | 69% | 2.44 | 226 / 328 | 1% | 0.01 | 1 / 178 |
| prostate | 67% | 2.25 | 165 / 245 | 2% | 0.02 | 8 / 502 |
| heart | 67% | 2.52 | 580 / 861 | 0% | 0 | 0 / 0 |
| kidney | 66% | 2.28 | 59 / 89 | 0% | 0.00 | 2 / 901 |
| peripheral blood | 66% | 5.26 | 611 / 929 | 0% | 0 | 0 / 0 |
| liver | 47% | 1.43 | 107 / 226 | 0% | 0.00 | 1 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0045446 | Biological process | endothelial cell differentiation |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0006334 | Biological process | nucleosome assembly |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005811 | Cellular component | lipid droplet |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0042393 | Molecular function | histone binding |
| GO_0003682 | Molecular function | chromatin binding |
| Gene name | SETSIP |
| Protein name | Protein SETSIP (SET pseudogene protein 18) (SET similar protein) (Similar to SET translocation protein) |
| Synonyms | SETP18 |
| Description | FUNCTION: Plays a role as a transcriptional activator involved in the early stage of somatic cell reprogramming. Promotes the differentiation of protein-induced pluripotent stem (PiPS) cells into endothelial cells and the formation of vascular-like tubes (in vitro). Involved in the transcription induction of vascular endothelial-cadherin (VE-cadherin) expression. Associates to the VE-cadherin gene promoter. . |
| Accessions | ENST00000596516.3 P0DME0 |