Name | Number of supported studies | Average coverage | |
---|---|---|---|
smooth muscle cell | 8 studies | 21% ± 4% | |
pericyte | 6 studies | 25% ± 14% | |
fibroblast | 6 studies | 25% ± 9% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 20% ± 4% | |
classical monocyte | 4 studies | 23% ± 5% | |
myofibroblast cell | 4 studies | 26% ± 16% | |
endothelial cell | 4 studies | 29% ± 4% | |
natural killer cell | 3 studies | 21% ± 4% | |
conventional dendritic cell | 3 studies | 24% ± 6% | |
non-classical monocyte | 3 studies | 35% ± 11% | |
epithelial cell | 3 studies | 38% ± 8% | |
dendritic cell | 3 studies | 40% ± 15% | |
endothelial cell of vascular tree | 3 studies | 21% ± 7% | |
basal cell | 3 studies | 27% ± 8% | |
connective tissue cell | 3 studies | 20% ± 3% |
Insufficient scRNA-seq data for expression of SERTAD3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1847.73 | 1445 / 1445 | 100% | 28.15 | 183 / 183 |
ovary | 100% | 1463.14 | 180 / 180 | 100% | 46.88 | 430 / 430 |
prostate | 100% | 1757.26 | 245 / 245 | 100% | 67.26 | 502 / 502 |
thymus | 100% | 1549.37 | 653 / 653 | 100% | 59.93 | 605 / 605 |
uterus | 100% | 1814.01 | 170 / 170 | 100% | 72.22 | 459 / 459 |
kidney | 100% | 1367.81 | 89 / 89 | 100% | 43.29 | 900 / 901 |
breast | 100% | 1816.85 | 459 / 459 | 100% | 93.42 | 1116 / 1118 |
bladder | 100% | 1817.48 | 21 / 21 | 100% | 59.90 | 503 / 504 |
lung | 100% | 1783.37 | 577 / 578 | 100% | 60.06 | 1154 / 1155 |
stomach | 100% | 1458.03 | 359 / 359 | 100% | 36.01 | 285 / 286 |
intestine | 100% | 1894.40 | 966 / 966 | 100% | 41.99 | 525 / 527 |
skin | 100% | 1277.59 | 1809 / 1809 | 100% | 36.73 | 470 / 472 |
adrenal gland | 100% | 1129.62 | 258 / 258 | 100% | 54.09 | 229 / 230 |
liver | 99% | 647.10 | 223 / 226 | 95% | 26.82 | 387 / 406 |
pancreas | 79% | 364.93 | 259 / 328 | 99% | 72.93 | 177 / 178 |
brain | 75% | 335.15 | 1969 / 2642 | 82% | 22.34 | 577 / 705 |
adipose | 100% | 2001.08 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1967.52 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 45.11 | 29 / 29 |
muscle | 100% | 1060.94 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1779.78 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 60.56 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 65.90 | 1 / 1 |
peripheral blood | 100% | 1789.28 | 925 / 929 | 0% | 0 | 0 / 0 |
heart | 100% | 1297.70 | 857 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 27.36 | 79 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0030308 | Biological process | negative regulation of cell growth |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
Gene name | SERTAD3 |
Protein name | SERTA domain-containing protein 3 (Replication protein-binding trans-activator) (RPA-binding trans-activator) SERTA domain containing 3 |
Synonyms | RBT1 |
Description | FUNCTION: Antiviral interferon-stimulated protein that plays a role in innate immunity and in the suppression of viruses through different mechanisms . Plays a role in the late phase response of TLR-induced immune effector expression (By similarity). During influenza infection, interacts with PB2, PB1, and PA to disrupt the formation of the viral RdRp complex . Inhibits zika virus by interacting with the capsid protein in the nucleolus and reducing its abundance through proteasomal degradation . Strong transcriptional coactivator . . |
Accessions | ENST00000599706.1 ENST00000596456.1 Q9UJW9 ENST00000322354.4 M0R352 ENST00000392028.8 M0QXL4 |