SERPINI1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007422Biological processperipheral nervous system development
GO_0010976Biological processpositive regulation of neuron projection development
GO_0010951Biological processnegative regulation of endopeptidase activity
GO_0007417Biological processcentral nervous system development
GO_0043204Cellular componentperikaryon
GO_0005615Cellular componentextracellular space
GO_0060205Cellular componentcytoplasmic vesicle lumen
GO_0070062Cellular componentextracellular exosome
GO_0043025Cellular componentneuronal cell body
GO_0034774Cellular componentsecretory granule lumen
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity

IV. Literature review

[source]
Gene nameSERPINI1
Protein nameSerpin peptidase inhibitor clade I member 1 isoform 2
Neuroserpin (Peptidase inhibitor 12) (PI-12) (Serpin I1)
Serpin family I member 1
Serpin peptidase inhibitor clade I member 1 isoform 1
SynonymsPI12
DescriptionFUNCTION: Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin . May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable). .

AccessionsENST00000446050.7
H7C5T9
ENST00000466865.1
ENST00000472941.5
C9JDY5
A0A0S2Z455
A0A0S2Z463
ENST00000295777.9
ENST00000472747.2
Q99574
C9JQU8