I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hepatocyte | 3 studies | 40% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| hepatocyte | 3 studies | 40% ± 6% |
Insufficient scRNA-seq data for expression of SERPINA10 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 21820.92 | 226 / 226 | 97% | 106.38 | 392 / 406 |
| pancreas | 99% | 32.10 | 325 / 328 | 13% | 2.19 | 23 / 178 |
| stomach | 83% | 30.34 | 298 / 359 | 27% | 1.29 | 78 / 286 |
| ovary | 100% | 162.16 | 180 / 180 | 0% | 0 | 0 / 430 |
| lung | 95% | 48.42 | 549 / 578 | 4% | 0.28 | 51 / 1155 |
| uterus | 86% | 37.22 | 147 / 170 | 2% | 0.04 | 9 / 459 |
| brain | 83% | 23.92 | 2188 / 2642 | 0% | 0 | 0 / 705 |
| prostate | 80% | 17.92 | 195 / 245 | 0% | 0.00 | 1 / 502 |
| skin | 72% | 15.18 | 1297 / 1809 | 1% | 0.01 | 3 / 472 |
| kidney | 70% | 9.72 | 62 / 89 | 1% | 0.09 | 9 / 901 |
| intestine | 44% | 6.05 | 422 / 966 | 24% | 1.57 | 129 / 527 |
| breast | 57% | 26.97 | 260 / 459 | 5% | 0.16 | 61 / 1118 |
| esophagus | 43% | 5.67 | 626 / 1445 | 12% | 0.85 | 22 / 183 |
| thymus | 53% | 6.16 | 345 / 653 | 0% | 0 | 0 / 605 |
| bladder | 43% | 3.71 | 9 / 21 | 9% | 0.32 | 46 / 504 |
| adrenal gland | 40% | 4.73 | 102 / 258 | 0% | 0.02 | 1 / 230 |
| adipose | 31% | 6.02 | 374 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 29% | 3.62 | 383 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 23% | 24.58 | 55 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 23% | 9.37 | 212 / 929 | 0% | 0 | 0 / 0 |
| heart | 15% | 1.67 | 133 / 861 | 0% | 0 | 0 / 0 |
| muscle | 6% | 0.62 | 51 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0060046 | Biological process | regulation of acrosome reaction |
| GO_0097421 | Biological process | liver regeneration |
| GO_0007596 | Biological process | blood coagulation |
| GO_0010951 | Biological process | negative regulation of endopeptidase activity |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0008201 | Molecular function | heparin binding |
| GO_0004867 | Molecular function | serine-type endopeptidase inhibitor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SERPINA10 |
| Protein name | Protein Z-dependent protease inhibitor (PZ-dependent protease inhibitor) (PZI) (Serpin A10) Protein Z-dependent protease inhibitor (Serpin family A member 10) (Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 10, isoform CRA_a) |
| Synonyms | hCG_22331 ZPI UNQ707/PRO1358 |
| Description | FUNCTION: Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors. . |
| Accessions | G3V2W1 ENST00000616057.2 Q9UK55 ENST00000261994.9 ENST00000393096.5 ENST00000614630.4 ENST00000554723.5 ENST00000554173.1 |
