SERF1A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SERF1A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SERF1A at tissue level.

III. Associated gene sets

GO_1990000Biological processamyloid fibril formation
GO_0031648Biological processprotein destabilization
GO_0007399Biological processnervous system development
GO_0032991Cellular componentprotein-containing complex
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameSERF1A
Protein nameSmall EDRK-rich factor 1
Small EDRK-rich factor 1 (Small EDRK-rich factor 1B)
Small EDRK-rich factor 1 (Protein 4F5) (h4F5) (SMA modifier 1)
SynonymsSERF1
SMAM1
FAM2B
SMAM1;
FAM2A
SERF1B
DescriptionFUNCTION: Positive regulator of amyloid protein aggregation and proteotoxicity . Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates . .

AccessionsENST00000380750.8 [O75920-1]
ENST00000515588.1
ENST00000611277.1
ENST00000354833.7 [O75920-1]
ENST00000622553.4 [O75920-1]
ENST00000622047.1
ENST00000613172.4 [O75920-1]
ENST00000626049.1
ENST00000380751.10 [O75920-2]
ENST00000611616.4 [O75920-2]
ENST00000614527.4 [O75920-1]
E5RIQ9
ENST00000614310.2
ENST00000317633.14 [O75920-2]
ENST00000512649.1
ENST00000630567.1 [O75920-1]
ENST00000503931.5
ENST00000611952.1
ENST00000629958.2
ENST00000630603.2
ENST00000621283.3 [O75920-2]
ENST00000630348.1
ENST00000628126.2
D6RC42
O75920
ENST00000507348.5
ENST00000504458.1
D6RCL9
ENST00000613176.4
ENST00000627372.2 [O75920-2]
ENST00000628888.2