SEPTIN8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0035542Biological processregulation of SNARE complex assembly
GO_0008104Biological processprotein localization
GO_0061640Biological processcytoskeleton-dependent cytokinesis
GO_0030424Cellular componentaxon
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0098793Cellular componentpresynapse
GO_0032153Cellular componentcell division site
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0031105Cellular componentseptin complex
GO_0005940Cellular componentseptin ring
GO_0005525Molecular functionGTP binding
GO_0003924Molecular functionGTPase activity
GO_0005515Molecular functionprotein binding
GO_0060090Molecular functionmolecular adaptor activity

IV. Literature review

[source]
Gene nameSEPTIN8
Protein nameSeptin 8
Septin
Septin-8
SynonymsKIAA0202
SEPT8
DescriptionFUNCTION: Filament-forming cytoskeletal GTPase (By similarity). May play a role in platelet secretion . Seems to participate in the process of SNARE complex formation in synaptic vesicles (By similarity). .; FUNCTION: [Isoform 4]: Stabilizes BACE1 protein levels and promotes the sorting and accumulation of BACE1 to the recycling or endosomal compartments, modulating the beta-amyloidogenic processing of APP. .

FUNCTION: Filament-forming cytoskeletal GTPase. .

FUNCTION: Filament-forming cytoskeletal GTPase. .

FUNCTION: Filament-forming cytoskeletal GTPase. .

FUNCTION: Filament-forming cytoskeletal GTPase. .

FUNCTION: Filament-forming cytoskeletal GTPase. .

AccessionsENST00000378719.7 [Q92599-1]
ENST00000453480.5
ENST00000296873.11 [Q92599-2]
ENST00000371493.7
A0A087X142
Q92599
ENST00000378706.5
A6NFQ9
F8W8I8
ENST00000458488.2 [Q92599-4]
ENST00000378701.5
ENST00000448933.5 [Q92599-3]
ENST00000620483.4
A6NMH6
B7ZVZ1
C9J4G8
ENST00000378721.8
Q3YL86
A0A0A0MRP8
ENST00000414594.5
C9JV02
ENST00000378699.6 [Q92599-3]