SENP8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SENP8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SENP8 at tissue level.

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0000338Biological processprotein deneddylation
GO_0043687Biological processpost-translational protein modification
GO_0005829Cellular componentcytosol
GO_0019784Molecular functiondeNEDDylase activity
GO_0008234Molecular functioncysteine-type peptidase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSENP8
Protein nameSUMO peptidase family member, NEDD8 specific
Sentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)
SynonymsNEDP1
PRSC2
FKSG8
DEN1
DescriptionFUNCTION: Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. .

AccessionsENST00000564863.5
H3BTK5
Q96LD8
H3BS71
ENST00000340912.6
H3BTJ8
ENST00000567794.5
ENST00000542035.2
ENST00000564082.1