SEMG1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SEMG1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SEMG1 at tissue level.

III. Associated gene sets

GO_0050817Biological processcoagulation
GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0031640Biological processkilling of cells of another organism
GO_0007320Biological processinsemination
GO_1901318Biological processnegative regulation of flagellated sperm motility
GO_0048240Biological processsperm capacitation
GO_0090281Biological processnegative regulation of calcium ion import
GO_1900005Biological processpositive regulation of serine-type endopeptidase activity
GO_0019731Biological processantibacterial humoral response
GO_0005615Cellular componentextracellular space
GO_0032991Cellular componentprotein-containing complex
GO_0070062Cellular componentextracellular exosome
GO_0005576Cellular componentextracellular region
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameSEMG1
Protein nameSEMG1 protein
Semenogelin I
Semenogelin-1 (Cancer/testis antigen 103) (Semenogelin I) (SGI) [Cleaved into: Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein]
SynonymsSEMG
DescriptionFUNCTION: Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA. .; FUNCTION: Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone. .

AccessionsQ6Y806
Q6Y808
P04279
ENST00000372781.4 [P04279-1]
A0JLP2