SEMA6B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071526Biological processsemaphorin-plexin signaling pathway
GO_0021766Biological processhippocampus development
GO_0030335Biological processpositive regulation of cell migration
GO_0001755Biological processneural crest cell migration
GO_0007411Biological processaxon guidance
GO_0050919Biological processnegative chemotaxis
GO_0007417Biological processcentral nervous system development
GO_0005886Cellular componentplasma membrane
GO_0045499Molecular functionchemorepellent activity
GO_0030215Molecular functionsemaphorin receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSEMA6B
Protein nameSemaphorin 6B isoform 2
Semaphorin 6B
Semaphorin-6B (Semaphorin-Z) (Sema Z)
SynonymsSEMAN
UNQ1907/PRO4353
SEMAZ
DescriptionFUNCTION: Functions as a cell surface repellent for mossy fibers of developing neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons. .; FUNCTION: (Microbial infection) Acts as a receptor for P.sordellii toxin TcsL in the in the vascular endothelium. .

AccessionsENST00000586582.6 [Q9H3T3-1]
ENST00000586965.1 [Q9H3T3-3]
ENST00000677828.1
Q9BXR8
Q9H3T3
A0A7I2V374
ENST00000676793.1 [Q9H3T3-1]