SEC24C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006886Biological processintracellular protein transport
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0001701Biological processin utero embryonic development
GO_0090110Biological processCOPII-coated vesicle cargo loading
GO_0012507Cellular componentER to Golgi transport vesicle membrane
GO_0005829Cellular componentcytosol
GO_0030127Cellular componentCOPII vesicle coat
GO_0070971Cellular componentendoplasmic reticulum exit site
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0000149Molecular functionSNARE binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameSEC24C
Protein nameSEC24 homolog C, COPII coat complex component (SEC24 related gene family, member C (S. cerevisiae), isoform CRA_b)
SEC24 homolog C, COPII coat complex component
Protein transport protein Sec24C (SEC24-related protein C)
SynonymsKIAA0079
hCG_19035
DescriptionFUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex . Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B . May more specifically package GPI-anchored proteins through the cargo receptor TMED10 . May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 . .

AccessionsG5EA31
ENST00000345254.9 [P53992-1]
ENST00000634508.1
ENST00000339365.2 [P53992-1]
ENST00000635550.1
A0A0U1RR58
A0A0U1RR49
ENST00000465076.5
P53992