SEC16B report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SEC16B at tissue level.

III. Associated gene sets

GO_0007029Biological processendoplasmic reticulum organization
GO_0010628Biological processpositive regulation of gene expression
GO_0015031Biological processprotein transport
GO_0006914Biological processautophagy
GO_0007030Biological processGolgi organization
GO_0070973Biological processprotein localization to endoplasmic reticulum exit site
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0070863Biological processpositive regulation of protein exit from endoplasmic reticulum
GO_0007031Biological processperoxisome organization
GO_0016559Biological processperoxisome fission
GO_0048208Biological processCOPII vesicle coating
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0012507Cellular componentER to Golgi transport vesicle membrane
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0070971Cellular componentendoplasmic reticulum exit site
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSEC16B
Protein nameSEC16 homolog B, endoplasmic reticulum export factor
Protein transport protein sec16
Protein transport protein Sec16B (Leucine zipper transcription regulator 2) (Regucalcin gene promoter region-related protein p117) (RGPR-p117) (SEC16 homolog B)
SynonymsSEC16S
KIAA1928
RGPR
LZTR2
DescriptionFUNCTION: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus . Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes . .

FUNCTION: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. .

AccessionsU3KQ39
Q96JE7
ENST00000527976.1
ENST00000528461.5
H0YE70
ENST00000464631.6
ENST00000308284.11 [Q96JE7-1]
E9PK14