SCO2 | OmnibusX

Name	Number of supported studies	Average coverage
classical monocyte	7 studies	24% ± 5%	Explore
non-classical monocyte	4 studies	30% ± 6%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SCO2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	85.39	1442 / 1445	68%	2.81	125 / 183
uterus	98%	51.81	166 / 170	49%	2.11	225 / 459
bladder	100%	50.90	21 / 21	40%	1.40	202 / 504
stomach	99%	51.78	354 / 359	40%	1.16	113 / 286
intestine	100%	91.50	964 / 966	38%	1.47	199 / 527
lung	100%	142.14	578 / 578	37%	0.91	422 / 1155
kidney	99%	98.53	88 / 89	26%	0.54	238 / 901
pancreas	90%	30.67	296 / 328	30%	0.56	54 / 178
skin	100%	91.19	1806 / 1809	21%	0.37	97 / 472
breast	100%	78.44	459 / 459	17%	0.36	186 / 1118
liver	100%	86.11	226 / 226	11%	0.18	44 / 406
thymus	98%	59.51	640 / 653	12%	0.29	70 / 605
prostate	99%	55.04	242 / 245	4%	0.06	22 / 502
adrenal gland	100%	90.67	258 / 258	2%	0.03	5 / 230
spleen	100%	112.11	241 / 241	0%	0	0 / 0
adipose	100%	100.56	1200 / 1204	0%	0	0 / 0
muscle	98%	48.36	790 / 803	0%	0	0 / 0
heart	98%	61.04	840 / 861	0%	0	0 / 0
ovary	67%	19.31	120 / 180	31%	0.53	132 / 430
peripheral blood	97%	120.53	903 / 929	0%	0	0 / 0
blood vessel	95%	47.37	1270 / 1335	0%	0	0 / 0
brain	89%	39.77	2348 / 2642	6%	0.11	41 / 705
tonsil	0%	0	0 / 0	64%	3.25	29 / 45
lymph node	0%	0	0 / 0	52%	1.25	15 / 29
eye	0%	0	0 / 0	9%	0.12	7 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0003012	Biological process	muscle system process
GO_0033617	Biological process	mitochondrial cytochrome c oxidase assembly
GO_0006878	Biological process	intracellular copper ion homeostasis
GO_0014823	Biological process	response to activity
GO_0001701	Biological process	in utero embryonic development
GO_0022904	Biological process	respiratory electron transport chain
GO_0001654	Biological process	eye development
GO_0030016	Cellular component	myofibril
GO_0005759	Cellular component	mitochondrial matrix
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0015035	Molecular function	protein-disulfide reductase activity
GO_0005507	Molecular function	copper ion binding
GO_0005515	Molecular function	protein binding
GO_0016531	Molecular function	copper chaperone activity

Gene name	SCO2
Protein name	Protein SCO2 homolog, mitochondrial Synthesis of cytochrome C oxidase 2
Synonyms
Description	FUNCTION: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 . Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2 . .
Accessions	ENST00000395693.8 ENST00000638598.2 ENST00000535425.5 O43819 ENST00000543927.6 ENST00000252785.3 A0A1W2PQK0

SCO2 report