I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 31% ± 7% | |
| dendritic cell | 3 studies | 24% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 31% ± 7% | |
| dendritic cell | 3 studies | 24% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 19% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1996.56 | 1445 / 1445 | 100% | 10.30 | 183 / 183 |
| lung | 100% | 1692.71 | 578 / 578 | 100% | 8.99 | 1155 / 1155 |
| ovary | 100% | 1455.68 | 180 / 180 | 100% | 7.16 | 430 / 430 |
| stomach | 100% | 1725.42 | 359 / 359 | 100% | 11.85 | 286 / 286 |
| intestine | 100% | 2411.45 | 966 / 966 | 100% | 11.23 | 526 / 527 |
| uterus | 100% | 2041.85 | 170 / 170 | 100% | 9.45 | 458 / 459 |
| brain | 100% | 1385.96 | 2633 / 2642 | 100% | 10.76 | 705 / 705 |
| breast | 100% | 2036.97 | 459 / 459 | 100% | 10.62 | 1114 / 1118 |
| bladder | 100% | 2110.19 | 21 / 21 | 100% | 9.65 | 502 / 504 |
| prostate | 100% | 1972.04 | 245 / 245 | 100% | 12.47 | 500 / 502 |
| thymus | 100% | 2131.71 | 653 / 653 | 99% | 8.49 | 601 / 605 |
| pancreas | 100% | 953.74 | 327 / 328 | 99% | 8.19 | 177 / 178 |
| liver | 100% | 2161.27 | 226 / 226 | 99% | 7.32 | 401 / 406 |
| kidney | 100% | 2112.04 | 89 / 89 | 99% | 10.79 | 888 / 901 |
| skin | 100% | 2177.20 | 1809 / 1809 | 98% | 10.21 | 464 / 472 |
| adrenal gland | 100% | 2440.48 | 258 / 258 | 94% | 7.19 | 216 / 230 |
| adipose | 100% | 2168.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 10.42 | 29 / 29 |
| muscle | 100% | 1865.98 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2037.59 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 9.18 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.58 | 1 / 1 |
| blood vessel | 100% | 1876.28 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 1728.08 | 846 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 6.49 | 75 / 80 |
| peripheral blood | 82% | 1234.86 | 759 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0033617 | Biological process | mitochondrial cytochrome c oxidase assembly |
| GO_0006878 | Biological process | intracellular copper ion homeostasis |
| GO_0030016 | Cellular component | myofibril |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005507 | Molecular function | copper ion binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016531 | Molecular function | copper chaperone activity |
| Gene name | SCO1 |
| Protein name | Protein SCO1 homolog, mitochondrial Synthesis of cytochrome C oxidase 1 |
| Synonyms | SCOD1 |
| Description | FUNCTION: Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 . Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1 (By similarity). . |
| Accessions | J3QL56 O75880 ENST00000255390.10 ENST00000577427.1 ENST00000577335.2 J3QR42 |
