Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 5 studies | 32% ± 14% | |
| GABAergic neuron | 4 studies | 37% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 25% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 6560.64 | 2621 / 2642 | 97% | 19.23 | 681 / 705 |
| thymus | 11% | 50.59 | 69 / 653 | 83% | 5.75 | 505 / 605 |
| heart | 71% | 718.73 | 610 / 861 | 0% | 0 | 0 / 0 |
| ovary | 5% | 20.76 | 9 / 180 | 58% | 2.47 | 249 / 430 |
| adrenal gland | 3% | 17.34 | 7 / 258 | 48% | 4.09 | 110 / 230 |
| intestine | 44% | 288.63 | 424 / 966 | 5% | 0.12 | 25 / 527 |
| lung | 28% | 147.01 | 159 / 578 | 21% | 0.49 | 237 / 1155 |
| uterus | 35% | 178.78 | 60 / 170 | 11% | 0.71 | 52 / 459 |
| prostate | 9% | 38.88 | 21 / 245 | 38% | 0.75 | 189 / 502 |
| muscle | 36% | 353.08 | 290 / 803 | 0% | 0 | 0 / 0 |
| pancreas | 0% | 0 | 0 / 328 | 35% | 0.86 | 62 / 178 |
| breast | 6% | 26.29 | 27 / 459 | 22% | 0.53 | 251 / 1118 |
| esophagus | 16% | 78.24 | 235 / 1445 | 8% | 0.13 | 15 / 183 |
| stomach | 4% | 15.70 | 14 / 359 | 9% | 0.19 | 25 / 286 |
| kidney | 0% | 0 | 0 / 89 | 8% | 0.49 | 69 / 901 |
| eye | 0% | 0 | 0 / 0 | 6% | 0.24 | 5 / 80 |
| bladder | 0% | 0 | 0 / 21 | 5% | 0.10 | 23 / 504 |
| skin | 0% | 0.87 | 3 / 1809 | 4% | 0.21 | 20 / 472 |
| adipose | 2% | 10.25 | 29 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.05 | 1 / 45 |
| blood vessel | 1% | 3.50 | 9 / 1335 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 0% | 0.02 | 2 / 406 |
| peripheral blood | 0% | 1.16 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0086012 | Biological process | membrane depolarization during cardiac muscle cell action potential |
| GO_2000649 | Biological process | regulation of sodium ion transmembrane transporter activity |
| GO_0009408 | Biological process | response to heat |
| GO_0086002 | Biological process | cardiac muscle cell action potential involved in contraction |
| GO_0098915 | Biological process | membrane repolarization during ventricular cardiac muscle cell action potential |
| GO_0060048 | Biological process | cardiac muscle contraction |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0046684 | Biological process | response to pyrethroid |
| GO_0060371 | Biological process | regulation of atrial cardiac muscle cell membrane depolarization |
| GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
| GO_0010467 | Biological process | gene expression |
| GO_0007399 | Biological process | nervous system development |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030315 | Cellular component | T-tubule |
| GO_0045202 | Cellular component | synapse |
| GO_0001518 | Cellular component | voltage-gated sodium channel complex |
| GO_0086006 | Molecular function | voltage-gated sodium channel activity involved in cardiac muscle cell action potential |
| GO_1902282 | Molecular function | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization |
| GO_0017080 | Molecular function | sodium channel regulator activity |
| Gene name | SCN2B |
| Protein name | Sodium channel subunit beta-2 Sodium voltage-gated channel beta subunit 2 Sodium channel, voltage-gated, type II, beta |
| Synonyms | hCG_41149 UNQ326/PRO386 |
| Description | FUNCTION: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity). . |
| Accessions | ENST00000658882.1 A0A590UJS3 Q5U0K8 O60939 ENST00000278947.6 |