Insufficient scRNA-seq data for expression of SCLY at single-cell level.
Insufficient scRNA-seq data for expression of SCLY at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 686.23 | 1444 / 1445 | 48% | 0.87 | 87 / 183 |
| stomach | 100% | 527.58 | 359 / 359 | 35% | 0.54 | 101 / 286 |
| intestine | 100% | 856.46 | 966 / 966 | 34% | 0.50 | 178 / 527 |
| liver | 100% | 2203.41 | 226 / 226 | 19% | 0.28 | 77 / 406 |
| brain | 100% | 807.40 | 2637 / 2642 | 17% | 0.22 | 119 / 705 |
| ovary | 100% | 699.55 | 180 / 180 | 16% | 0.23 | 67 / 430 |
| lung | 99% | 569.29 | 575 / 578 | 12% | 0.18 | 139 / 1155 |
| kidney | 100% | 1256.02 | 89 / 89 | 11% | 0.16 | 101 / 901 |
| bladder | 100% | 878.67 | 21 / 21 | 11% | 0.19 | 55 / 504 |
| skin | 100% | 571.78 | 1802 / 1809 | 11% | 0.16 | 53 / 472 |
| uterus | 100% | 1004.58 | 170 / 170 | 9% | 0.14 | 43 / 459 |
| pancreas | 100% | 1465.97 | 328 / 328 | 3% | 0.04 | 5 / 178 |
| breast | 100% | 585.29 | 459 / 459 | 3% | 0.04 | 28 / 1118 |
| adrenal gland | 100% | 449.03 | 258 / 258 | 2% | 0.03 | 5 / 230 |
| prostate | 100% | 740.55 | 245 / 245 | 2% | 0.03 | 10 / 502 |
| thymus | 100% | 972.14 | 653 / 653 | 1% | 0.01 | 4 / 605 |
| adipose | 100% | 568.28 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 798.11 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 677.47 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 415.55 | 797 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 502.50 | 837 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 91% | 663.28 | 850 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.16 | 4 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 0.05 | 2 / 45 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.01 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006520 | Biological process | amino acid metabolic process |
| GO_0016261 | Biological process | selenocysteine catabolic process |
| GO_1902494 | Cellular component | catalytic complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0016597 | Molecular function | amino acid binding |
| GO_0016740 | Molecular function | transferase activity |
| GO_0070279 | Molecular function | vitamin B6 binding |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0009000 | Molecular function | selenocysteine lyase activity |
| Gene name | SCLY |
| Protein name | Selenocysteine lyase Alternative protein SCLY Selenocysteine lyase (hSCL) (EC 4.4.1.16) Selenocysteine lyase (EC 4.4.1.16) |
| Synonyms | hCG_2039445 SCL |
| Description | FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . FUNCTION: Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. . |
| Accessions | ENST00000433750.1 C9JNL5 ENST00000443532.5 ENST00000423324.5 ENST00000651534.1 ENST00000413463.6 ENST00000440143.1 ENST00000409736.6 [Q96I15-2] H7C1N7 H7C277 F8WBU3 L8E8S1 A0A0A0MQU4 Q96I15 H7C4A1 ENST00000437134.5 ENST00000416757.1 H7C2M1 H7C3V9 B4DDP9 ENST00000450965.5 ENST00000412508.6 F8WCL3 ENST00000254663.12 [Q96I15-1] H7C280 ENST00000446202.5 H7C2H3 |