SCGB3A2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SCGB3A2 at tissue level.

III. Associated gene sets

GO_0005576Cellular componentextracellular region
GO_0005615Cellular componentextracellular space
GO_0071682Cellular componentendocytic vesicle lumen

IV. Literature review

[source]
Gene nameSCGB3A2
Protein nameSecretoglobin, family 3A, member 2 (Uteroglobin related protein 1)
Secretoglobin family 3A member 2 (Pneumo secretory protein 1) (PnSP-1) (Uteroglobin-related protein 1)
Secretoglobin family 3A member 2
SynonymsUNQ566/PRO1128
PNSP1
UGRP1
hCG_1645642
DescriptionFUNCTION: Secreted cytokine-like protein . Binds to the scavenger receptor MARCO . Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast . Strongly inhibits phospholipase A2 (PLA2G1B) activity . Seems to have anti-inflammatory effects in respiratory epithelium (By similarity). Also has anti-fibrotic activity in lung . May play a role in fetal lung development and maturation . Promotes branching morphogenesis during early stages of lung development . In the pituitary, may inhibit production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (By similarity). .

AccessionsENST00000504320.5
ENST00000296694.5
D6RBX5
Q96PL1
Q2L6B3