SCD5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006636Biological processunsaturated fatty acid biosynthetic process
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0016491Molecular functionoxidoreductase activity
GO_0046872Molecular functionmetal ion binding
GO_0004768Molecular functionstearoyl-CoA 9-desaturase activity

IV. Literature review

[source]
Gene nameSCD5
Protein nameSCD5 protein
SCD5 protein (Stearoyl-CoA desaturase 5, isoform CRA_d)
Stearoyl-CoA desaturase 5 (EC 1.14.19.1) (Acyl-CoA-desaturase 4) (HSCD5) (Stearoyl-CoA 9-desaturase) (Stearoyl-CoA desaturase 2)
SynonymsSCD4
SCD2
hCG_1782054
ACOD4
DescriptionFUNCTION: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA . Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids . Involved in neuronal cell proliferation and differentiation through down-regulation of EGFR/AKT/MAPK and Wnt signaling pathways . .

AccessionsENST00000319540.9 [Q86SK9-1]
Q86UC8
Q86SK9
ENST00000273908.4 [Q86SK9-2]
Q9BSN4