I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 17% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 17% ± 2% |
Insufficient scRNA-seq data for expression of SBF1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 10372.62 | 1445 / 1445 | 100% | 64.19 | 183 / 183 |
| skin | 100% | 11015.48 | 1808 / 1809 | 100% | 60.85 | 470 / 472 |
| thymus | 100% | 24549.45 | 653 / 653 | 99% | 59.40 | 601 / 605 |
| intestine | 100% | 9931.45 | 966 / 966 | 99% | 44.75 | 523 / 527 |
| uterus | 100% | 9697.96 | 170 / 170 | 99% | 39.46 | 454 / 459 |
| brain | 100% | 16083.04 | 2631 / 2642 | 99% | 74.21 | 700 / 705 |
| stomach | 100% | 7209.06 | 359 / 359 | 99% | 46.92 | 282 / 286 |
| kidney | 100% | 7630.39 | 89 / 89 | 99% | 32.93 | 888 / 901 |
| prostate | 100% | 9621.93 | 245 / 245 | 98% | 30.31 | 493 / 502 |
| bladder | 100% | 8704.19 | 21 / 21 | 98% | 33.84 | 494 / 504 |
| pancreas | 100% | 6879.30 | 327 / 328 | 98% | 38.26 | 175 / 178 |
| lung | 99% | 8764.70 | 575 / 578 | 97% | 38.40 | 1125 / 1155 |
| breast | 100% | 7844.76 | 458 / 459 | 95% | 25.16 | 1064 / 1118 |
| adrenal gland | 100% | 8092.66 | 258 / 258 | 92% | 46.77 | 212 / 230 |
| ovary | 100% | 9105.02 | 180 / 180 | 92% | 23.62 | 394 / 430 |
| liver | 82% | 2934.04 | 185 / 226 | 79% | 16.19 | 320 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 44.52 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 54.95 | 29 / 29 |
| muscle | 100% | 11618.55 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 10281.95 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 58.74 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 15.89 | 1 / 1 |
| adipose | 100% | 7556.67 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 9275.32 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 7744.26 | 898 / 929 | 0% | 0 | 0 / 0 |
| heart | 94% | 5670.26 | 812 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0007286 | Biological process | spermatid development |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005829 | Cellular component | cytosol |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0016791 | Molecular function | phosphatase activity |
| GO_0008138 | Molecular function | protein tyrosine/serine/threonine phosphatase activity |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| Gene name | SBF1 |
| Protein name | SBF1 protein Myotubularin-related protein 5 (Inactive phosphatidylinositol 3-phosphatase 5) (SET-binding factor 1) (Sbf1) SET binding factor 1 |
| Synonyms | hCG_16879 MTMR5 |
| Description | FUNCTION: Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location . May function as a guanine nucleotide exchange factor (GEF) activating RAB28 . Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form . Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts . . |
| Accessions | A0A8I5KVF2 ENST00000686222.1 ENST00000692946.1 A0A8I5KUL5 A0A8I5KNQ5 ENST00000691792.1 A0A8I5QKT8 ENST00000685239.1 ENST00000687340.1 A0A8I5KWI8 ENST00000692076.1 ENST00000686801.1 ENST00000688124.1 A0A8I5KUE4 A0A8I5KTN1 ENST00000689849.1 ENST00000348911.11 ENST00000685459.1 ENST00000418590.4 ENST00000688381.1 A0A8I5KXX9 A0A8I5KU87 ENST00000691233.1 A0A8I5KT25 A0A8J8YTQ8 ENST00000688030.1 ENST00000685386.1 ENST00000689981.1 ENST00000687016.1 ENST00000689095.1 ENST00000684986.1 [O95248-4] ENST00000693440.1 ENST00000690990.1 A0A8I5KVL6 A0A8I5KY28 A0A8I5KUU6 A0A8I5KW56 A0A8I5KTI7 ENST00000688985.1 A0A8I5KT60 A0A8I5KZ29 O95248 H0Y5W8 A0A8I5KX98 ENST00000691306.1 ENST00000686321.1 ENST00000693068.1 A0A8I5KYT4 A0A8I5KU03 A0A8I5KS44 A0A8I5KY61 ENST00000690197.1 A0A8I5KRX8 ENST00000380817.8 [O95248-5] A0A8I5KYG9 A0A8I5KWB4 A0A8I5KR05 ENST00000685592.1 ENST00000688066.1 A0A8I5QJN2 ENST00000688848.1 A0A8I5KS51 ENST00000686427.1 A0A8I5KS97 A0A8I5KVI6 ENST00000686029.1 ENST00000689129.1 [O95248-1] A0A8I5KXH4 ENST00000687878.1 ENST00000691344.1 Q6PGN5 ENST00000692006.1 ENST00000693052.1 A0A8I5KS68 A0A8I5QKN6 ENST00000687704.1 ENST00000685809.1 Q86TK5 A0A8I5KPS7 ENST00000686421.1 A0A8I5KUS0 ENST00000686717.1 A0A8I5KXX8 A0A8I5KXN1 |
