I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 20% ± 2% | |
| transit amplifying cell | 3 studies | 32% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 20% ± 2% | |
| transit amplifying cell | 3 studies | 32% ± 17% |
Insufficient scRNA-seq data for expression of SASS6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 291.19 | 1444 / 1445 | 99% | 11.35 | 182 / 183 |
| ovary | 100% | 321.25 | 180 / 180 | 98% | 7.70 | 423 / 430 |
| breast | 100% | 295.29 | 459 / 459 | 98% | 8.48 | 1095 / 1118 |
| uterus | 100% | 385.59 | 170 / 170 | 97% | 10.90 | 444 / 459 |
| bladder | 100% | 274.19 | 21 / 21 | 96% | 7.23 | 486 / 504 |
| lung | 99% | 223.96 | 570 / 578 | 97% | 7.08 | 1118 / 1155 |
| intestine | 100% | 352.29 | 966 / 966 | 95% | 6.64 | 501 / 527 |
| stomach | 99% | 244.18 | 356 / 359 | 95% | 7.70 | 273 / 286 |
| prostate | 100% | 298.43 | 245 / 245 | 93% | 4.79 | 467 / 502 |
| brain | 98% | 226.47 | 2599 / 2642 | 91% | 3.91 | 640 / 705 |
| skin | 100% | 307.43 | 1802 / 1809 | 82% | 5.41 | 389 / 472 |
| pancreas | 99% | 155.28 | 325 / 328 | 81% | 3.40 | 145 / 178 |
| thymus | 100% | 283.42 | 653 / 653 | 77% | 2.93 | 468 / 605 |
| kidney | 100% | 173.55 | 89 / 89 | 65% | 2.23 | 583 / 901 |
| liver | 95% | 126.86 | 215 / 226 | 48% | 2.05 | 196 / 406 |
| adrenal gland | 98% | 221.79 | 253 / 258 | 34% | 1.10 | 79 / 230 |
| spleen | 100% | 398.78 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 10.71 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.09 | 1 / 1 |
| adipose | 100% | 235.97 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 206.91 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 95% | 145.58 | 763 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 6.82 | 27 / 29 |
| heart | 93% | 132.83 | 799 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 64% | 404.45 | 590 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 20% | 0.55 | 16 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1900087 | Biological process | positive regulation of G1/S transition of mitotic cell cycle |
| GO_0060236 | Biological process | regulation of mitotic spindle organization |
| GO_0046601 | Biological process | positive regulation of centriole replication |
| GO_1905832 | Biological process | positive regulation of spindle assembly |
| GO_0007099 | Biological process | centriole replication |
| GO_0051298 | Biological process | centrosome duplication |
| GO_0005814 | Cellular component | centriole |
| GO_0120099 | Cellular component | procentriole replication complex |
| GO_0005813 | Cellular component | centrosome |
| GO_0098536 | Cellular component | deuterosome |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SASS6 |
| Protein name | Spindle assembly abnormal protein 6 homolog (HsSAS-6) SASS6 protein |
| Synonyms | SAS6 |
| Description | FUNCTION: Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification . . |
| Accessions | ENST00000287482.6 Q495U0 Q6UVJ0 |
