Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 15 studies | 65% ± 24% | |
| glutamatergic neuron | 11 studies | 38% ± 19% | |
| GABAergic neuron | 8 studies | 34% ± 13% | |
| endothelial cell | 6 studies | 33% ± 15% | |
| mast cell | 6 studies | 30% ± 12% | |
| interneuron | 5 studies | 37% ± 20% | |
| retina horizontal cell | 5 studies | 66% ± 22% | |
| neuron | 4 studies | 25% ± 5% | |
| microglial cell | 4 studies | 34% ± 17% | |
| GABAergic interneuron | 3 studies | 37% ± 21% | |
| epithelial cell | 3 studies | 35% ± 18% | |
| granule cell | 3 studies | 43% ± 27% | |
| oligodendrocyte precursor cell | 3 studies | 22% ± 1% | |
| GABAergic amacrine cell | 3 studies | 44% ± 5% | |
| oligodendrocyte | 3 studies | 34% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 13 studies | 33% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 97% | 3593.48 | 2567 / 2642 | 63% | 3.14 | 445 / 705 |
| uterus | 98% | 3595.58 | 167 / 170 | 12% | 0.53 | 56 / 459 |
| prostate | 82% | 770.80 | 202 / 245 | 18% | 0.26 | 88 / 502 |
| muscle | 100% | 5194.94 | 800 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 94% | 1478.71 | 1260 / 1335 | 0% | 0 | 0 / 0 |
| bladder | 90% | 1437.29 | 19 / 21 | 4% | 0.08 | 18 / 504 |
| esophagus | 78% | 1290.61 | 1132 / 1445 | 13% | 0.39 | 24 / 183 |
| breast | 83% | 954.02 | 380 / 459 | 7% | 0.17 | 76 / 1118 |
| kidney | 73% | 549.53 | 65 / 89 | 13% | 0.50 | 117 / 901 |
| intestine | 77% | 2108.83 | 743 / 966 | 2% | 0.03 | 10 / 527 |
| adipose | 65% | 612.16 | 782 / 1204 | 0% | 0 | 0 / 0 |
| skin | 47% | 350.86 | 844 / 1809 | 3% | 0.07 | 15 / 472 |
| adrenal gland | 41% | 275.43 | 107 / 258 | 7% | 0.18 | 16 / 230 |
| stomach | 42% | 677.12 | 150 / 359 | 5% | 0.12 | 14 / 286 |
| spleen | 45% | 290.80 | 108 / 241 | 0% | 0 | 0 / 0 |
| ovary | 37% | 395.17 | 67 / 180 | 5% | 0.11 | 22 / 430 |
| thymus | 22% | 127.88 | 145 / 653 | 11% | 0.49 | 66 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 27% | 1.27 | 12 / 45 |
| lung | 12% | 85.35 | 71 / 578 | 13% | 0.34 | 146 / 1155 |
| eye | 0% | 0 | 0 / 0 | 8% | 0.24 | 6 / 80 |
| pancreas | 0% | 1.34 | 1 / 328 | 3% | 0.05 | 6 / 178 |
| heart | 2% | 15.47 | 18 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.95 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006941 | Biological process | striated muscle contraction |
| GO_0019722 | Biological process | calcium-mediated signaling |
| GO_0006874 | Biological process | intracellular calcium ion homeostasis |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0071286 | Biological process | cellular response to magnesium ion |
| GO_0071318 | Biological process | cellular response to ATP |
| GO_0071277 | Biological process | cellular response to calcium ion |
| GO_0071313 | Biological process | cellular response to caffeine |
| GO_0014808 | Biological process | release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| GO_0006816 | Biological process | calcium ion transport |
| GO_0070588 | Biological process | calcium ion transmembrane transport |
| GO_0051289 | Biological process | protein homotetramerization |
| GO_0016020 | Cellular component | membrane |
| GO_0030018 | Cellular component | Z disc |
| GO_0005790 | Cellular component | smooth endoplasmic reticulum |
| GO_0042383 | Cellular component | sarcolemma |
| GO_0034704 | Cellular component | calcium channel complex |
| GO_0033017 | Cellular component | sarcoplasmic reticulum membrane |
| GO_0048763 | Molecular function | calcium-induced calcium release activity |
| GO_0005219 | Molecular function | ryanodine-sensitive calcium-release channel activity |
| GO_0015278 | Molecular function | intracellularly gated calcium channel activity |
| GO_0005516 | Molecular function | calmodulin binding |
| GO_0005509 | Molecular function | calcium ion binding |
| Gene name | RYR3 |
| Protein name | Ryanodine receptor 3 Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor) |
| Synonyms | HBRR |
| Description | FUNCTION: Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction . May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling. . |
| Accessions | ENST00000415757.7 [Q15413-2] ENST00000637948.1 ENST00000634730.1 A0A1B0GTF2 A0A0X1KG73 ENST00000389232.9 ENST00000638032.1 ENST00000634418.1 A0A1B0GTT7 A0A1B0GVS2 Q15413 ENST00000636845.1 ENST00000634750.1 ENST00000635842.1 ENST00000622037.1 A0A087X080 ENST00000634891.2 [Q15413-1] A0A0U1RRH1 A0A1B0GVA9 ENST00000636568.1 A0A1B0GU27 A0A0U1RR21 A0A1B0GUB0 ENST00000635790.1 A0A0U1RR54 |