RYR3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006941Biological processstriated muscle contraction
GO_0019722Biological processcalcium-mediated signaling
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0051209Biological processrelease of sequestered calcium ion into cytosol
GO_0071286Biological processcellular response to magnesium ion
GO_0071318Biological processcellular response to ATP
GO_0071277Biological processcellular response to calcium ion
GO_0071313Biological processcellular response to caffeine
GO_0014808Biological processrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO_0006816Biological processcalcium ion transport
GO_0070588Biological processcalcium ion transmembrane transport
GO_0051289Biological processprotein homotetramerization
GO_0016020Cellular componentmembrane
GO_0030018Cellular componentZ disc
GO_0005790Cellular componentsmooth endoplasmic reticulum
GO_0042383Cellular componentsarcolemma
GO_0034704Cellular componentcalcium channel complex
GO_0033017Cellular componentsarcoplasmic reticulum membrane
GO_0048763Molecular functioncalcium-induced calcium release activity
GO_0005219Molecular functionryanodine-sensitive calcium-release channel activity
GO_0015278Molecular functionintracellularly gated calcium channel activity
GO_0005516Molecular functioncalmodulin binding
GO_0005509Molecular functioncalcium ion binding

IV. Literature review

[source]
Gene nameRYR3
Protein nameRyanodine receptor 3
Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)
SynonymsHBRR
DescriptionFUNCTION: Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction . May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling. .

AccessionsENST00000415757.7 [Q15413-2]
ENST00000637948.1
ENST00000634730.1
A0A1B0GTF2
A0A0X1KG73
ENST00000389232.9
ENST00000638032.1
ENST00000634418.1
A0A1B0GTT7
A0A1B0GVS2
Q15413
ENST00000636845.1
ENST00000634750.1
ENST00000635842.1
ENST00000622037.1
A0A087X080
ENST00000634891.2 [Q15413-1]
A0A0U1RRH1
A0A1B0GVA9
ENST00000636568.1
A0A1B0GU27
A0A0U1RR21
A0A1B0GUB0
ENST00000635790.1
A0A0U1RR54