RXFP4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of RXFP4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RXFP4 at tissue level.

III. Associated gene sets

GO_0007218Biological processneuropeptide signaling pathway
GO_2000253Biological processpositive regulation of feeding behavior
GO_0005886Cellular componentplasma membrane
GO_0008528Molecular functionG protein-coupled peptide receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRXFP4
Protein nameRelaxin-3 receptor 2 (RLN3 receptor 2) (G-protein coupled receptor 100) (G-protein coupled receptor GPCR142) (Insulin-like peptide INSL5 receptor) (Relaxin family peptide receptor 4)
SynonymsGPR100
GPCR142
RLN3R2
DescriptionFUNCTION: High affinity receptor for INSL5. Also acts as a receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. .

AccessionsQ8TDU9
ENST00000368318.5