RXFP2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of RXFP2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RXFP2 at tissue level.

III. Associated gene sets

GO_0001556Biological processoocyte maturation
GO_0008584Biological processmale gonad development
GO_0007190Biological processactivation of adenylate cyclase activity
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0043066Biological processnegative regulation of apoptotic process
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007193Biological processadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO_0043950Biological processpositive regulation of cAMP-mediated signaling
GO_0009755Biological processhormone-mediated signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0016500Molecular functionprotein-hormone receptor activity
GO_0008528Molecular functionG protein-coupled peptide receptor activity
GO_0017046Molecular functionpeptide hormone binding

IV. Literature review

[source]
Gene nameRXFP2
Protein nameRelaxin receptor 2 (G-protein coupled receptor 106) (G-protein coupled receptor affecting testicular descent) (Leucine-rich repeat-containing G-protein coupled receptor 8) (Relaxin family peptide receptor 2)
SynonymsLGR8
GREAT
GPR106
DescriptionFUNCTION: Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).

AccessionsQ8WXD0
ENST00000380314.2 [Q8WXD0-2]
ENST00000298386.7 [Q8WXD0-1]