Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 5 studies | 23% ± 4% | |
| astrocyte | 5 studies | 23% ± 6% | |
| GABAergic neuron | 5 studies | 30% ± 13% | |
| oligodendrocyte | 5 studies | 20% ± 4% | |
| glutamatergic neuron | 4 studies | 45% ± 14% | |
| interneuron | 4 studies | 30% ± 17% | |
| microglial cell | 3 studies | 19% ± 3% | |
| epithelial cell | 3 studies | 22% ± 5% | |
| fibroblast | 3 studies | 27% ± 8% | |
| macrophage | 3 studies | 33% ± 16% | |
| oligodendrocyte precursor cell | 3 studies | 26% ± 6% | |
| neuron | 3 studies | 29% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 33% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1328.28 | 2640 / 2642 | 100% | 41.96 | 705 / 705 |
| breast | 100% | 1312.49 | 459 / 459 | 100% | 23.68 | 1116 / 1118 |
| prostate | 100% | 1310.46 | 245 / 245 | 100% | 23.05 | 500 / 502 |
| thymus | 100% | 1528.63 | 653 / 653 | 100% | 29.60 | 602 / 605 |
| ovary | 100% | 1553.59 | 180 / 180 | 99% | 16.03 | 426 / 430 |
| kidney | 100% | 1020.58 | 89 / 89 | 99% | 17.79 | 891 / 901 |
| bladder | 100% | 1264.05 | 21 / 21 | 99% | 16.25 | 498 / 504 |
| adrenal gland | 100% | 1197.42 | 258 / 258 | 99% | 32.11 | 227 / 230 |
| lung | 100% | 1085.75 | 578 / 578 | 99% | 15.31 | 1139 / 1155 |
| uterus | 100% | 1487.38 | 170 / 170 | 98% | 18.60 | 452 / 459 |
| pancreas | 99% | 500.55 | 324 / 328 | 98% | 16.72 | 175 / 178 |
| intestine | 100% | 1088.40 | 966 / 966 | 97% | 11.97 | 511 / 527 |
| esophagus | 100% | 926.10 | 1445 / 1445 | 96% | 11.19 | 176 / 183 |
| skin | 100% | 1049.08 | 1809 / 1809 | 96% | 16.28 | 451 / 472 |
| stomach | 100% | 829.87 | 359 / 359 | 93% | 11.58 | 267 / 286 |
| liver | 98% | 380.27 | 221 / 226 | 81% | 8.22 | 330 / 406 |
| adipose | 100% | 1143.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1329.18 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 13.71 | 29 / 29 |
| spleen | 100% | 1011.20 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.84 | 1 / 1 |
| muscle | 100% | 636.58 | 799 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 662.72 | 834 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 12.03 | 43 / 45 |
| eye | 0% | 0 | 0 / 0 | 91% | 13.89 | 73 / 80 |
| peripheral blood | 59% | 303.58 | 552 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1990253 | Biological process | cellular response to leucine starvation |
| GO_0009267 | Biological process | cellular response to starvation |
| GO_0034198 | Biological process | cellular response to amino acid starvation |
| GO_0071230 | Biological process | cellular response to amino acid stimulus |
| GO_0010507 | Biological process | negative regulation of autophagy |
| GO_0008104 | Biological process | protein localization |
| GO_1904263 | Biological process | positive regulation of TORC1 signaling |
| GO_0032006 | Biological process | regulation of TOR signaling |
| GO_0032008 | Biological process | positive regulation of TOR signaling |
| GO_0005764 | Cellular component | lysosome |
| GO_1990131 | Cellular component | Gtr1-Gtr2 GTPase complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0051020 | Molecular function | GTPase binding |
| GO_0005525 | Molecular function | GTP binding |
| GO_0032561 | Molecular function | guanyl ribonucleotide binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | RRAGB |
| Protein name | Ras-related GTP-binding protein Ras-related GTP-binding protein B (Rag B) (RagB) (EC 3.6.5.-) |
| Synonyms | |
| Description | FUNCTION: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade . Forms heterodimeric Rag complexes with RagC/RRAGC or RagD/RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form: RagB/RRAGB is in its active form when GTP-bound RagB/RRAGB forms a complex with GDP-bound RagC/RRAGC (or RagD/RRAGD) and in an inactive form when GDP-bound RagB/RRAGB heterodimerizes with GTP-bound RagC/RRAGC (or RagD/RRAGD) . In its GTP-bound active form, promotes the recruitment of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB . Involved in the RCC1/Ran-GTPase pathway . . FUNCTION: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. . |
| Accessions | ENST00000414239.5 Q5VZM2 ENST00000262850.7 [Q5VZM2-1] ENST00000374941.9 [Q5VZM2-2] Q5VZM0 |