RPP40 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of RPP40 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RPP40 at tissue level.

III. Associated gene sets

GO_0000447Biological processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0001682Biological processtRNA 5'-leader removal
GO_0030681Cellular componentmultimeric ribonuclease P complex
GO_0000172Cellular componentribonuclease MRP complex
GO_0005655Cellular componentnucleolar ribonuclease P complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0033204Molecular functionribonuclease P RNA binding
GO_0000171Molecular functionribonuclease MRP activity
GO_0005515Molecular functionprotein binding
GO_0004526Molecular functionribonuclease P activity

IV. Literature review

[source]
Gene nameRPP40
Protein nameRibonuclease P/MRP subunit p40
Ribonuclease P protein subunit p40 (RNaseP protein p40) (RNase P subunit 1)
Ribonuclease P 40kDa subunit, isoform CRA_c (Ribonuclease P/MRP subunit p40)
Alternative protein RPP40
SynonymsRNASEP1
hCG_1783141
DescriptionFUNCTION: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends . Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences . .

AccessionsENST00000479782.1
ENST00000319533.9 [O75818-2]
ENST00000464646.1
L8E9F2
ENST00000618533.4
F8WC38
X6RLL4
O75818
A0A087X1N3
ENST00000380051.7 [O75818-1]