Insufficient scRNA-seq data for expression of ROPN1B at single-cell level.
Insufficient scRNA-seq data for expression of ROPN1B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 70% | 136.66 | 1272 / 1809 | 95% | 13.15 | 449 / 472 |
| prostate | 64% | 37.23 | 158 / 245 | 62% | 1.76 | 309 / 502 |
| brain | 93% | 86.02 | 2469 / 2642 | 18% | 0.31 | 128 / 705 |
| thymus | 87% | 43.47 | 571 / 653 | 6% | 0.10 | 37 / 605 |
| eye | 0% | 0 | 0 / 0 | 91% | 9.22 | 73 / 80 |
| breast | 61% | 157.92 | 278 / 459 | 27% | 4.27 | 297 / 1118 |
| heart | 84% | 50.48 | 719 / 861 | 0% | 0 | 0 / 0 |
| uterus | 44% | 12.89 | 74 / 170 | 22% | 0.59 | 99 / 459 |
| adrenal gland | 26% | 7.21 | 67 / 258 | 26% | 0.51 | 59 / 230 |
| ovary | 38% | 9.81 | 68 / 180 | 3% | 0.04 | 14 / 430 |
| bladder | 33% | 9.14 | 7 / 21 | 7% | 0.14 | 37 / 504 |
| liver | 27% | 8.24 | 60 / 226 | 8% | 0.16 | 34 / 406 |
| lung | 22% | 8.09 | 125 / 578 | 12% | 0.26 | 138 / 1155 |
| muscle | 33% | 11.06 | 267 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 33% | 10.62 | 435 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 18% | 0.43 | 8 / 45 |
| intestine | 14% | 3.87 | 138 / 966 | 1% | 0.02 | 6 / 527 |
| pancreas | 8% | 1.89 | 26 / 328 | 6% | 0.08 | 10 / 178 |
| kidney | 10% | 2.51 | 9 / 89 | 0% | 0.00 | 2 / 901 |
| esophagus | 6% | 2.26 | 89 / 1445 | 3% | 0.04 | 5 / 183 |
| stomach | 4% | 0.90 | 14 / 359 | 2% | 0.05 | 5 / 286 |
| adipose | 5% | 4.99 | 61 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 4% | 0.85 | 10 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.20 | 4 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007266 | Biological process | Rho protein signal transduction |
| GO_0061512 | Biological process | protein localization to cilium |
| GO_0061640 | Biological process | cytoskeleton-dependent cytokinesis |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0030317 | Biological process | flagellated sperm motility |
| GO_0001932 | Biological process | regulation of protein phosphorylation |
| GO_0007342 | Biological process | fusion of sperm to egg plasma membrane involved in single fertilization |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0044782 | Biological process | cilium organization |
| GO_0048240 | Biological process | sperm capacitation |
| GO_0007340 | Biological process | acrosome reaction |
| GO_0031514 | Cellular component | motile cilium |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0030159 | Molecular function | signaling receptor complex adaptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ROPN1B |
| Protein name | Rhophilin associated tail protein 1B Ropporin-1B (Rhophilin-associated protein 1B) |
| Synonyms | |
| Description | FUNCTION: Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. . FUNCTION: Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. . FUNCTION: Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. . FUNCTION: Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. . |
| Accessions | ENST00000508088.1 ENST00000505382.5 [Q9BZX4-2] Q9BZX4 ENST00000504401.1 ENST00000251776.8 [Q9BZX4-1] D6RCR2 D6RAA3 ENST00000511082.1 [Q9BZX4-2] D6RA85 ENST00000514116.6 [Q9BZX4-1] ENST00000513830.5 |