RNFT2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1904294Biological processpositive regulation of ERAD pathway
GO_0016020Cellular componentmembrane
GO_0046872Molecular functionmetal ion binding
GO_0061630Molecular functionubiquitin protein ligase activity

IV. Literature review

[source]
Gene nameRNFT2
Protein nameAlternative protein RNFT2
Ring finger protein, transmembrane 2
E3 ubiquitin-protein ligase RNFT2 (RING finger and transmembrane domain-containing protein 2) (Transmembrane protein 118)
SynonymsTMEM118
DescriptionFUNCTION: E3 ubiquitin-protein ligase that negatively regulates IL3-dependent cellular responses through IL3RA ubiquitination and degradation by the proteasome, having an anti-inflammatory effect. .

AccessionsENST00000407967.7 [Q96EX2-5]
F8VZS7
Q96EX2
L8EAK7
ENST00000392549.7 [Q96EX2-1]
ENST00000677328.1
ENST00000547718.5
ENST00000257575.9 [Q96EX2-1]
A0A7I2V5U1