Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 14 studies | 23% ± 8% | |
fibroblast | 10 studies | 25% ± 8% | |
adipocyte | 9 studies | 31% ± 9% | |
oligodendrocyte | 9 studies | 26% ± 7% | |
microglial cell | 7 studies | 24% ± 6% | |
astrocyte | 7 studies | 36% ± 16% | |
epithelial cell | 5 studies | 23% ± 4% | |
GABAergic neuron | 5 studies | 43% ± 20% | |
macrophage | 5 studies | 32% ± 7% | |
endothelial cell of lymphatic vessel | 4 studies | 21% ± 5% | |
smooth muscle cell | 4 studies | 18% ± 2% | |
basal cell | 3 studies | 25% ± 7% | |
club cell | 3 studies | 19% ± 4% | |
hepatocyte | 3 studies | 42% ± 13% | |
glutamatergic neuron | 3 studies | 64% ± 4% | |
oligodendrocyte precursor cell | 3 studies | 24% ± 6% | |
interneuron | 3 studies | 51% ± 21% | |
neuron | 3 studies | 37% ± 15% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 7 studies | 37% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 3327.04 | 653 / 653 | 94% | 6.84 | 571 / 605 |
uterus | 100% | 2800.31 | 170 / 170 | 92% | 7.35 | 421 / 459 |
ovary | 100% | 3936.58 | 180 / 180 | 88% | 4.40 | 377 / 430 |
lung | 100% | 3603.62 | 578 / 578 | 86% | 8.23 | 990 / 1155 |
kidney | 93% | 965.40 | 83 / 89 | 89% | 6.05 | 802 / 901 |
prostate | 100% | 2219.30 | 244 / 245 | 80% | 2.94 | 403 / 502 |
breast | 100% | 3197.00 | 459 / 459 | 76% | 4.32 | 854 / 1118 |
pancreas | 90% | 824.29 | 294 / 328 | 84% | 4.27 | 149 / 178 |
esophagus | 100% | 2520.69 | 1445 / 1445 | 73% | 12.31 | 134 / 183 |
adrenal gland | 100% | 1492.04 | 258 / 258 | 71% | 3.73 | 164 / 230 |
liver | 99% | 1513.03 | 223 / 226 | 69% | 3.16 | 282 / 406 |
bladder | 100% | 2831.14 | 21 / 21 | 64% | 4.57 | 322 / 504 |
brain | 83% | 713.81 | 2192 / 2642 | 80% | 2.82 | 562 / 705 |
stomach | 100% | 1720.85 | 358 / 359 | 51% | 2.29 | 146 / 286 |
intestine | 99% | 3080.68 | 958 / 966 | 49% | 2.27 | 260 / 527 |
skin | 100% | 3242.04 | 1809 / 1809 | 46% | 1.86 | 216 / 472 |
adipose | 100% | 3324.33 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4344.19 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 1296.69 | 793 / 803 | 0% | 0 | 0 / 0 |
spleen | 95% | 851.12 | 228 / 241 | 0% | 0 | 0 / 0 |
heart | 92% | 1211.78 | 788 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 6.15 | 40 / 45 |
peripheral blood | 5% | 33.17 | 47 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 5% | 0.12 | 4 / 80 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.08 | 1 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0000151 | Cellular component | ubiquitin ligase complex |
GO_0005829 | Cellular component | cytosol |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0008270 | Molecular function | zinc ion binding |
GO_0031624 | Molecular function | ubiquitin conjugating enzyme binding |
Gene name | RNF217 |
Protein name | Ring finger protein 217 E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.31) (IBR domain-containing protein 1) (Opposite STL) (RING finger protein 217) RBR-type E3 ubiquitin transferase (EC 2.3.2.31) |
Synonyms | IBRDC1 OSTL C6orf172 |
Description | FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis. . |
Accessions | ENST00000519565.5 ENST00000432158.6 E5RFY6 ENST00000368414.6 H0YB95 Q8TC41 ENST00000359704.2 [Q8TC41-2] H0YKH8 ENST00000521654.7 [Q8TC41-1] H3BM17 ENST00000560949.5 |