RNF207 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of RNF207 at tissue level.

III. Associated gene sets

GO_1901207Biological processregulation of heart looping
GO_0010628Biological processpositive regulation of gene expression
GO_1902261Biological processpositive regulation of delayed rectifier potassium channel activity
GO_0086019Biological processcell-cell signaling involved in cardiac conduction
GO_1903762Biological processpositive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO_0055117Biological processregulation of cardiac muscle contraction
GO_1903954Biological processpositive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0051087Molecular functionprotein-folding chaperone binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0030544Molecular functionHsp70 protein binding
GO_0044325Molecular functiontransmembrane transporter binding

IV. Literature review

[source]
Gene nameRNF207
Protein nameRING finger protein 207
SynonymsC1orf188
DescriptionFUNCTION: Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner. .

AccessionsQ6ZRF8
ENST00000377939.5 [Q6ZRF8-1]