RNF182 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	7 studies	30% ± 11%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of RNF182 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	1153.91	2613 / 2642	98%	24.25	688 / 705
thymus	86%	137.22	559 / 653	37%	1.94	221 / 605
lung	99%	528.83	573 / 578	16%	1.46	188 / 1155
ovary	22%	33.01	39 / 180	70%	7.27	302 / 430
kidney	57%	121.13	51 / 89	33%	2.24	296 / 901
skin	23%	52.14	416 / 1809	61%	10.54	289 / 472
adipose	73%	137.88	882 / 1204	0%	0	0 / 0
breast	45%	59.78	206 / 459	12%	1.49	133 / 1118
uterus	18%	31.49	30 / 170	31%	6.06	140 / 459
peripheral blood	26%	85.41	244 / 929	0%	0	0 / 0
bladder	5%	4.33	1 / 21	20%	1.79	100 / 504
prostate	23%	32.77	57 / 245	0%	0.03	2 / 502
intestine	5%	5.22	48 / 966	13%	0.99	71 / 527
pancreas	11%	13.59	37 / 328	6%	1.02	11 / 178
stomach	2%	1.98	8 / 359	13%	1.89	37 / 286
esophagus	5%	5.96	75 / 1445	9%	1.09	17 / 183
adrenal gland	1%	2.21	3 / 258	10%	0.62	24 / 230
tonsil	0%	0	0 / 0	7%	1.36	3 / 45
spleen	6%	13.54	15 / 241	0%	0	0 / 0
blood vessel	6%	8.01	78 / 1335	0%	0	0 / 0
liver	0%	0	0 / 226	4%	0.25	15 / 406
heart	4%	4.41	31 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	3%	0.11	2 / 80
muscle	1%	1.71	12 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

Gene name	RNF182
Protein name	Ring finger protein 182 E3 ubiquitin-protein ligase RNF182 (EC 2.3.2.27) (RING finger protein 182) (RING-type E3 ubiquitin transferase RNF182)
Synonyms
Description	FUNCTION: E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway . Also plays a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA . .
Accessions	C9IZ30 ENST00000544682.5 ENST00000488763.5 C9JAJ3 ENST00000471906.1 ENST00000537663.5 C9JVS8 Q8N6D2 ENST00000488300.6 ENST00000537388.1 ENST00000420478.2 C9JAK6 ENST00000423553.6

GO_0016567	Biological process	protein ubiquitination
GO_0016020	Cellular component	membrane
GO_0005737	Cellular component	cytoplasm
GO_0004842	Molecular function	ubiquitin-protein transferase activity
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

RNF182 report