Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 8 studies | 27% ± 8% | |
endothelial cell | 6 studies | 25% ± 7% | |
epithelial cell | 5 studies | 29% ± 8% | |
astrocyte | 5 studies | 32% ± 9% | |
glutamatergic neuron | 5 studies | 44% ± 20% | |
GABAergic neuron | 4 studies | 43% ± 17% | |
oligodendrocyte precursor cell | 4 studies | 30% ± 8% | |
interneuron | 4 studies | 36% ± 21% | |
microglial cell | 3 studies | 18% ± 2% | |
retinal cone cell | 3 studies | 36% ± 14% | |
ciliated cell | 3 studies | 21% ± 5% | |
fibroblast | 3 studies | 18% ± 2% | |
basal cell | 3 studies | 24% ± 6% | |
goblet cell | 3 studies | 16% ± 1% | |
neuron | 3 studies | 30% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 2067.78 | 2642 / 2642 | 100% | 19.74 | 705 / 705 |
ovary | 100% | 1515.90 | 180 / 180 | 100% | 12.24 | 430 / 430 |
esophagus | 100% | 1085.46 | 1443 / 1445 | 100% | 12.92 | 183 / 183 |
thymus | 100% | 3111.95 | 653 / 653 | 100% | 27.03 | 604 / 605 |
uterus | 100% | 1365.04 | 170 / 170 | 100% | 10.93 | 458 / 459 |
stomach | 100% | 799.25 | 359 / 359 | 100% | 14.63 | 285 / 286 |
prostate | 100% | 1361.96 | 245 / 245 | 100% | 13.88 | 500 / 502 |
intestine | 100% | 1208.13 | 966 / 966 | 99% | 15.37 | 524 / 527 |
breast | 100% | 1181.34 | 458 / 459 | 100% | 17.26 | 1114 / 1118 |
kidney | 100% | 1286.34 | 89 / 89 | 99% | 15.63 | 894 / 901 |
bladder | 100% | 1301.67 | 21 / 21 | 99% | 11.99 | 500 / 504 |
adrenal gland | 100% | 1633.34 | 258 / 258 | 99% | 17.67 | 227 / 230 |
pancreas | 99% | 786.78 | 324 / 328 | 99% | 13.12 | 177 / 178 |
lung | 98% | 1041.14 | 566 / 578 | 100% | 14.64 | 1154 / 1155 |
liver | 99% | 827.42 | 224 / 226 | 96% | 10.65 | 388 / 406 |
skin | 100% | 1573.46 | 1809 / 1809 | 93% | 11.64 | 438 / 472 |
lymph node | 0% | 0 | 0 / 0 | 100% | 8.36 | 29 / 29 |
spleen | 100% | 1305.18 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 9.20 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 16.44 | 1 / 1 |
adipose | 100% | 1145.55 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 941.77 | 1327 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 795.08 | 793 / 803 | 0% | 0 | 0 / 0 |
heart | 96% | 710.62 | 829 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 84% | 7.63 | 67 / 80 |
peripheral blood | 58% | 429.91 | 540 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0070936 | Biological process | protein K48-linked ubiquitination |
GO_0034140 | Biological process | negative regulation of toll-like receptor 3 signaling pathway |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | RNF170 |
Protein name | E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (Putative LAG1-interacting protein) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170) Ring finger protein 170 |
Synonyms | |
Description | FUNCTION: E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. Selectively inhibits the TLR3-triggered innate immune response by promoting the 'Lys-48'-linked polyubiquitination and degradation of TLR3 . . |
Accessions | ENST00000524954.1 ENST00000526349.5 [Q96K19-6] E9PP55 ENST00000531440.5 ENST00000319073.5 [Q96K19-5] Q96K19 E9PNG8 ENST00000527424.6 [Q96K19-1] ENST00000319104.7 [Q96K19-3] ENST00000240159.8 [Q96K19-5] ENST00000534961.5 [Q96K19-1] |